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Enhanced antitumor effect of combined-modality treatment using convection-enhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts.
Author: KikuchiToshio, KumabeToshihiro, SonodaYukihiko, SugiyamaShin-Ichiro, TominagaTeiji, YamashitaYoji
Original Abstract of the Article :
Convection-enhanced delivery (CED) is a local infusion technique that delivers chemotherapeutic agents directly to the central nervous system, circumventing the blood-brain barrier and reducing systemic side effects. We previously reported the safety and efficacy of CED of ACNU (nimustine hydrochlor...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1179/174313208X331581
データ提供:米国国立医学図書館(NLM)
Combating Brain Tumors: Exploring Combined-Modality Treatment Approaches
Brain tumors are a complex challenge, and this study investigates combined-modality treatments, which is like a multi-pronged approach to tackling a difficult problem. The researchers are looking at the efficacy of combining convection-enhanced delivery (CED) of ACNU with irradiation or systemic administration of temozolomide in treating intracranial brain tumor xenografts. The study is a desert expedition, where researchers are exploring different routes and strategies to overcome the obstacles presented by brain tumors.Combined-Modality Treatment Shows Promise in Brain Tumor Therapy
The study's findings suggest that combined-modality treatments using CED of ACNU with irradiation or temozolomide may be an effective approach in treating intracranial brain tumors. The researchers are exploring the best way to use these tools to effectively attack the tumor, like a caravan navigating a desert to find the most efficient path to reach its destination.Navigating the Brain Tumor Desert: Combined-Modality Strategies for Treatment
This research provides valuable insights into the potential of combined-modality treatment for brain tumors. By understanding the effectiveness of different approaches, we can develop more targeted and effective treatments, like mapping a desert to find the best route to reach a vital oasis.Dr. Camel's Conclusion
This study opens a new avenue for brain tumor treatment, highlighting the potential of combined-modality approaches. It's like a desert explorer discovering a new oasis, offering a ray of hope for those facing this challenging diagnosis.Date :
- Date Completed 2008-12-22
- Date Revised 2018-12-01
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