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Desmopressin 30 years in clinical use: a safety review.

Author: NørgaardJens P, RaesAnn, StocknerMette, Vande WalleJohan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This paper reviews the safety of desmopressin, a synthetic analogue of the antidiuretic hormone arginine vasopressin, based on published data and adverse reactions reported to the manufacturer. Desmopressin is generally well tolerated with minor side effects, although there is a small risk of hyponatraemia.
Paper Details　
Original Abstract of the Article :
Desmopressin acetate is the synthetic analogue of the antidiuretic hormone arginine vasopressin. It has been employed clinically for >30 years in a range of formulations: intranasal solution (since 1972), injectable solution (since 1981), tablets (since 1987), and most recently, an oral lyophilisate...See full text at original site
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引用元：
https://doi.org/10.2174/157488607781668891

データ提供：米国国立医学図書館（NLM）

Desmopressin: A 30-Year Journey in Clinical Use

Greetings, my fellow researchers! It's Dr. Camel, and today, we're exploring the long and fruitful history of desmopressin, a medication used to treat various conditions, including nocturnal enuresis and diabetes insipidus.

This review, like a seasoned traveler recounting decades of experience, provides a comprehensive safety analysis of desmopressin, a medication that has been used for over 30 years. The authors, like skilled historians, meticulously document the safety profile of desmopressin, considering various formulations and clinical applications.

The review highlights the generally good tolerability of desmopressin, with most side effects being minor. However, the study emphasizes the importance of careful monitoring for potential hyponatremia, a condition that can occur with desmopressin use. It's like navigating a desert oasis with caution, ensuring that the water we drink is safe and balanced.

A Well-Established Treatment Option

This review provides a reassuring assessment of the safety profile of desmopressin, a medication with a long history of clinical use. It highlights the importance of careful monitoring for potential side effects, particularly hyponatremia, to ensure safe and effective treatment.

Living with Desmopressin Treatment

This review is a valuable resource for individuals taking desmopressin, providing insights into its safety profile and potential side effects. It emphasizes the importance of open communication with healthcare providers to ensure safe and effective treatment. Individuals using desmopressin should be aware of potential side effects and discuss any concerns with their physicians.

Dr.Camel's Conclusion

This review is a testament to the enduring value of desmopressin, a medication that has been used for decades to treat various conditions. The thorough safety analysis provides reassurance about its overall safety profile while emphasizing the importance of careful monitoring and open communication with healthcare providers. It's a reminder that even in the vast desert of medical treatments, some medications have stood the test of time, providing valuable solutions for patients.

Date :
  1. Date Completed 2008-09-02
  2. Date Revised 2019-11-11
Further Info :

Pubmed ID

18690973

DOI: Digital Object Identifier

10.2174/157488607781668891

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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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