In vitro and in vivo evaluations of oxacillin efficiency against mecA-positive oxacillin-susceptible Staphylococcus aureus.

Author: IkonomidisAlexandros, KaravasilisVasilis, LabrouMaria, ManiatisAntonios N, MichailGeorge, PournarasSpyros, StathopoulosConstantinos, VasdekiAfroditi

Paper Details 
Original Abstract of the Article :
Community-type Staphylococcus aureus strains that are positive for mecA and PBP2a but appear phenotypically susceptible to oxacillin are increasingly reported worldwide. Four S. aureus clinical isolates carrying the mecA gene with oxacillin MICs of <2 microg/ml were tested for oxacillin efficiency b...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573153/

データ提供:米国国立医学図書館(NLM)

In Vitro and In Vivo Evaluations of Oxacillin Efficiency Against mecA-Positive Oxacillin-Susceptible Staphylococcus aureus

This research explores the intricate world of antibiotic resistance, a challenge as daunting as navigating a desert landscape riddled with hidden dangers. The researchers investigated the effectiveness of oxacillin, a commonly used antibiotic, against certain strains of Staphylococcus aureus that are resistant to other antibiotics, much like finding a safe route through a desert region plagued by venomous snakes.

Combating the Desert Threat: Exploring Oxacillin's Effectiveness Against Resistant Bacteria

The study examined four clinical isolates of S. aureus that were positive for the mecA gene but still appeared susceptible to oxacillin. This is like searching for a specific type of desert plant that can withstand the harsh conditions and offer protection from the venomous snakes. The researchers found that some of these resistant strains were partially responsive to oxacillin, providing a glimmer of hope for treating these infections.

Navigating the Desert of Antibiotic Resistance: Seeking New Solutions

This research highlights the ongoing challenge of antibiotic resistance. The study underscores the need for continued research and development of new antibiotics and treatment strategies to combat this growing threat. This is like discovering new and more effective ways to navigate the desert, finding safe routes and protecting ourselves from the dangers that lurk within.

Dr.Camel's Conclusion

This research reminds us that the battle against antibiotic resistance is a constant struggle, much like the ongoing journey through a harsh desert landscape. We must be vigilant in our efforts to develop new antibiotics and treatment strategies to protect vulnerable populations from these potentially deadly infections.
Date :
  1. Date Completed 2009-01-21
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18694946

DOI: Digital Object Identifier

PMC2573153

Related Literature

SNS
PICO Info
in preparation
Languages

English

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