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Medical or surgical management of GERD patients with Barrett's esophagus: the LOTUS trial 3-year experience.

Author: AttwoodS E, EklundS, EllC, FioccaR, GalmicheJ-P, HatlebakkJ G, JunghardO, LindT, LundellL

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Laparoscopic antireflux surgery (LARS) was equally successful in patients with or without Barrett's esophagus (BE) and comparable to optimized medical therapy.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: The long-term management of gastroesophageal reflux in patients with Barrett's esophagus (BE) is not well supported by an evidence-based consensus. We compare treatment outcome in patients with and without BE submitted to standardized laparoscopic antireflux surgery (LARS) or esomepraz...See full text at original site
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引用元：
https://doi.org/10.1007/s11605-008-0645-1

データ提供：米国国立医学図書館（NLM）

Medical or Surgical Management of GERD Patients with Barrett's Esophagus: Navigating the Oasis of Treatment Options

Gastroesophageal reflux disease (GERD), like a persistent desert wind, can cause discomfort and long-term health complications. This study delves into the management of GERD patients with Barrett's esophagus (BE), a condition that increases the risk of esophageal cancer. The research compared the long-term outcomes of standardized laparoscopic antireflux surgery (LARS) with those of esomeprazole treatment, examining the effectiveness of both approaches in managing symptoms and preventing disease progression.

A Two-Pronged Approach: Surgical and Medical Management of GERD with BE

The study, like a well-traveled caravan route, explores two distinct paths to manage GERD with BE: surgery and medication. The results show that both LARS and esomeprazole can effectively control symptoms and prevent treatment failure in the long term. However, LARS demonstrated a better control of esophageal pH compared to esomeprazole, indicating a potential advantage for surgical intervention in managing GERD with BE.

Choosing the Right Oasis: Weighing the Options for GERD Management

The choice between surgical and medical management for GERD with BE, like choosing the best oasis in the desert, depends on individual factors, including symptoms, disease severity, and personal preferences. It's crucial to consult with a healthcare professional to determine the most appropriate treatment approach and to ensure a safe and effective course of care.

Dr.Camel's Conclusion

This research, like a well-mapped desert route, offers valuable insights into the management of GERD with BE. Both surgical and medical options can effectively manage symptoms and prevent treatment failure. Choosing the right approach requires careful consideration of individual factors and close collaboration with a healthcare professional. As a camel who has experienced many desert landscapes, I encourage patients to seek expert advice and make informed decisions about their treatment.

Date :
  1. Date Completed 2009-01-30
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18709511

DOI: Digital Object Identifier

10.1007/s11605-008-0645-1

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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