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Treatment of bipolar disorder: a systematic review of available data and clinical perspectives.

Author: FountoulakisKonstantinos N, VietaEduard

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review of research on bipolar disorder found that lithium is effective for both acute manic episodes and long-term management. First- and second-generation antipsychotics are effective for acute mania. Quetiapine and a combination of olanzapine and fluoxetine are effective for treating bipolar depression, while olanzapine, quetiapine, and aripiprazole are useful for long-term management. Anticonvulsants, particularly valproate and carbamazepine, help with mania, while lamotrigine might be more effective for depression. Antidepressants should always be used with other medications due to the risk of triggering manic episodes. The best psychological treatments are group and family psychoeducation. Electroconvulsive therapy can be used for patients who don't respond to other treatments. While many treatment options exist, they are not consistently effective, especially for depression and long-term management. Combining treatments may improve outcomes, but it can increase side effects. Further research is needed to develop more effective treatments and better guidelines.
Paper Details　
Original Abstract of the Article :
This paper is a systematic review of the available data concerning the treatment of bipolar disorder: a systematic Medline search concerning treatment guidelines and clinical trials. The search for treatment guidelines returned 583 articles and 913 papers for RCTs. The search was last performed on 1...See full text at original site
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引用元：
https://doi.org/10.1017/S1461145708009231

データ提供：米国国立医学図書館（NLM）

Navigating the Complexities of Bipolar Disorder Treatment

The field of [bipolar disorder treatment] is constantly seeking to refine and optimize treatment approaches. This study provides a comprehensive [systematic review of available data] on the treatment of bipolar disorder, including [treatment guidelines and clinical trials]. The authors present a detailed analysis of the efficacy of various medications, such as lithium, antipsychotics, anticonvulsants, and antidepressants, in treating both the manic and depressive phases of the disorder. The study also emphasizes the importance of [psychosocial interventions] and [electroconvulsive therapy (ECT)] for refractory cases.

Balancing Medications and Therapy: A Holistic Approach

This research highlights the need for a [holistic approach] to bipolar disorder treatment. The study emphasizes the importance of combining [pharmacological interventions] with [psychosocial therapies] to address the multifaceted nature of the disorder. This approach recognizes that effective treatment requires addressing not only the biological aspects of the disorder but also the psychological and social factors that contribute to its development and management.

Living with Bipolar Disorder: Strategies for Management

This research provides valuable insights for individuals living with bipolar disorder. The study highlights the importance of [early diagnosis] and [consistent treatment] to manage the symptoms and prevent episodes. It also emphasizes the need for [ongoing support] from family, friends, and healthcare professionals to navigate the challenges of living with this chronic condition.

Dr. Camel's Conclusion

This research underscores the complexities of bipolar disorder treatment. Like a desert landscape with shifting sands, the disorder can be unpredictable and challenging to manage. However, with the right combination of medication, therapy, and support, individuals can live fulfilling lives despite the challenges they face. Continued research and development of innovative treatment approaches are crucial to ensure that those affected by this disorder receive the best possible care.

Date :
  1. Date Completed 2008-12-08
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

18752718

DOI: Digital Object Identifier

10.1017/S1461145708009231

Related Literature

Article Analysis
・Effective treatment of bipolar disorder
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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