Role and relevance of PEPT2 in drug disposition, dynamics, and toxicity.

Author: KamalMohamed A, KeepRichard F, SmithDavid E

Paper Details 
Original Abstract of the Article :
Pept2 knockout mice are an important tool to evaluate the evolving role and relevance of this proton-coupled oligopeptide transporter beyond drug disposition, where the transporter also modulates the pharmacodynamic and toxicodynamic effects of drug substrates. Our in vivo studies with glycylsarcosi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/18762710

データ提供:米国国立医学図書館(NLM)

PEPT2: A Key Player in Drug Disposition, Dynamics, and Toxicity

The world of drug development is a vast and complex desert, where researchers constantly search for new pathways to understand and manipulate drug behavior. This research explores the crucial role of PEPT2, a proton-coupled oligopeptide transporter, in drug disposition, dynamics, and toxicity. This study, much like an explorer charting a new territory, reveals the intricate workings of this important transporter.

PEPT2's Influence on Drug Disposition and Toxicity: A Complex Landscape

The study highlights the significant effect PEPT2 can have on dipeptide disposition, drug pharmacology, and even toxicity. This research reveals the intricate interplay between PEPT2 and drug behavior, offering valuable insights into the complexities of drug development. This study, like a careful analysis of the desert landscape, uncovers the hidden pathways and influences that shape drug behavior.

PEPT2's Influence on Drug Disposition and Toxicity: A Complex Landscape

This research provides invaluable information for drug developers and researchers, helping them navigate the complex terrain of drug behavior. It emphasizes the importance of understanding PEPT2's role in drug disposition and toxicity, offering a deeper understanding of the factors influencing drug efficacy and safety. This research, much like a guidebook to the desert, provides essential knowledge for navigating the complexities of drug development.

Dr.Camel's Conclusion

This study unveils the intricate role of PEPT2 in shaping drug behavior. This research is like a guidebook to the desert of drug development, providing invaluable insights into the factors influencing drug disposition, dynamics, and toxicity. Understanding PEPT2's role is crucial for advancing drug development and ensuring the safe and effective use of medications.

Date :
  1. Date Completed 2008-11-18
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18762710

DOI: Digital Object Identifier

NIHMS210579

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.