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Intramuscular imipenem/cilastatin in multiple-dose treatment regimens: review of the worldwide clinical experience.

Author: CalandraG B, GarauJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

Intramuscular administration of imipenem/cilastatin was effective in treating various infections requiring multiple-dose therapy, with a favorable clinical outcome in 95% or more of evaluable patients. Side effects were similar in type but less common in frequency compared to the intravenous formulation.
Paper Details　
Original Abstract of the Article :
Multicenter noncomparative trials of intramuscular administration of imipenem/cilastatin for the treatment of a variety of infections requiring multiple-dose therapy are reviewed. Fourteen centers in the United States and 18 centers elsewhere participated in these studies. A total of 686 patients (4...See full text at original site
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引用元：
https://doi.org/10.1159/000238919

データ提供：米国国立医学図書館（NLM）

Intramuscular Imipenem/Cilastatin: A Powerful Weapon Against Infections

Infections, like a sandstorm in the desert, can be a serious threat to our health. Imipenem/cilastatin, a powerful antibiotic combination, can be a valuable weapon in fighting these infections. This research, like a camel caravan traversing the vast landscape of clinical trials, explores the effectiveness of intramuscular administration of imipenem/cilastatin in treating various infections. The research highlights the efficacy of this drug in treating a wide range of infections, including skin and soft tissue infections, intra-abdominal infections, and sepsis. The study also emphasizes the good tolerability of the intramuscular formulation, making it a valuable option for treating infections.

A Powerful Weapon in the Fight Against Infections

This research demonstrates the effectiveness of intramuscular imipenem/cilastatin in treating a wide range of infections. This finding is particularly important for patients who may not be suitable for intravenous administration.

Navigating Infections: A Powerful Tool

This research highlights the potential of intramuscular imipenem/cilastatin as a valuable tool in fighting infections. Its effectiveness and good tolerability make it a promising option for treating a variety of infections, offering a beacon of hope in the face of these health challenges.

Dr.Camel's Conclusion

This research, like a trusty camel caravan, navigates the challenging terrain of infectious diseases, showcasing the efficacy and tolerability of intramuscular imipenem/cilastatin. This powerful weapon against infections offers a valuable resource for healthcare professionals battling these sandstorms of illness.

Date :
  1. Date Completed 1991-10-01
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

1879187

DOI: Digital Object Identifier

10.1159/000238919

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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