Time-, schedule-, and reinforcer-dependent effects of pimozide and amphetamine.

Author: MuscatR, NunnJ, PhillipsG, SampsonD, WillnerP

Paper Details 
Original Abstract of the Article :
Rats performed on two multiple random-interval schedules, in which sequences of ascending or descending reinforcement densities were balanced between the schedules and between the two halves of the session. Using a standard reinforcer (10% sucrose pellets), pimozide decreased response rates, while a...See full text at original site
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引用元:
https://doi.org/10.1007/BF02244566

データ提供:米国国立医学図書館(NLM)

Pimozide, Amphetamine, and Reward: A Complex Desert Landscape

This research explores the fascinating and complex interplay between dopamine, reward, and the effects of psychoactive drugs, using rats as a model system. It's like studying the behavior of desert animals, observing how they react to different stimuli and resources.

Schedule- and Time-Dependent Effects

The study found that the effects of both pimozide and amphetamine were schedule- and time-dependent. This suggests that the impact of these drugs can vary depending on the context and duration of exposure. It's like watching a desert animal change its behavior based on the time of day and the availability of food and water.

Unraveling the Complexity of Reward

The study also revealed a complex relationship between reward, drug effects, and consumption. This highlights the need for further research to fully understand the nuances of reward processing and how it's affected by psychoactive drugs. It's like exploring a vast desert, where each dune and oasis represents a different aspect of reward and its influence on behavior.

Dr.Camel's Conclusion

This research delves into the intricate workings of the brain's reward system, highlighting the complex and often paradoxical effects of psychoactive drugs. It's like studying the diverse and ever-changing landscape of a desert, where each element plays a unique role in shaping the overall ecosystem. Further research is needed to unravel the complexities of reward and to develop more effective therapies for treating drug addiction and other related disorders.

Date :
  1. Date Completed 1991-09-30
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

1881998

DOI: Digital Object Identifier

10.1007/BF02244566

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Article Analysis
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PICO Info
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Languages

English

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