Postpartum severe sinus bradycardia following methylergonovine administration.

Author: IbrahimS M, LouonA, MustafaE

Paper Details 
Original Abstract of the Article :
The case is reported of a 30-year-old multigravida, with insignificant history and stable vital signs, admitted to the labour room for normal vaginal delivery of twins. She received combined spinal epidural analgesia (bupivacaine plus fentanyl) for 3 h. Following uneventful delivery she received 0.2...See full text at original site
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引用元:
https://doi.org/10.1177/147323000803600534

データ提供:米国国立医学図書館(NLM)

Methylergonovine: A Case of Unexpected Side Effects

Methylergonovine is a medication commonly used to prevent postpartum hemorrhage, but in rare cases, it can lead to unexpected side effects. This case report describes a 30-year-old woman who experienced severe sinus bradycardia following the administration of methylergonovine. The patient received methylergonovine after delivering twins via vaginal delivery. Within 70 minutes of receiving the medication, she developed nausea, vomiting, a decrease in heart rate, an increase in blood pressure, and chest pain. The patient was treated with atropine sulphate, which improved her chest pain but resulted in an unexpected increase in both heart rate and blood pressure. The case report highlights the potential for serious delayed side effects from methylergonovine, even in young and otherwise healthy patients. The authors emphasize the importance of close monitoring following methylergonovine administration and warn about the potential for paradoxical effects with atropine sulphate.

Methylergonovine: A Reminder of Potential Risks

This case report serves as a reminder of the potential for unexpected side effects from methylergonovine, even in patients with no prior history of medical complications. The findings emphasize the importance of close monitoring following methylergonovine administration and careful consideration of potential drug interactions, especially with atropine sulphate.

Managing Postpartum Hemorrhage: A Balanced Approach

This case report underscores the importance of a balanced approach to managing postpartum hemorrhage. While methylergonovine is an effective medication, it is crucial to be aware of potential risks and to closely monitor patients following its administration. As Dr. Camel, I always emphasize the importance of careful medication selection and monitoring for individual patients. This case report serves as a reminder of the need for vigilance in clinical practice.

Dr. Camel's Conclusion

This case report highlights the potential for serious, delayed side effects from methylergonovine, even in young, healthy patients. The findings underscore the importance of close monitoring following methylergonovine administration and careful consideration of potential drug interactions, particularly with atropine sulphate.

Date :
  1. Date Completed 2008-10-27
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

18831911

DOI: Digital Object Identifier

10.1177/147323000803600534

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SNS
PICO Info
in preparation
Languages

English

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