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Idiopathic thrombocytopenic purpura in elderly patients: a study of 47 cases from a single reference center.

Author: AndrèsEmmanuel, DaouSamira, FedericiLaure, MaloiselFrédéric, SerrajKhalid, ZimmerJacques

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This retrospective study reviewed the experience of managing idiopathic thrombocytopenic purpura (ITP) in 47 consecutive elderly patients (> or =60 years old). The results confirm that age influences the hemorrhagic pattern, response to therapy, and adverse effects of conventional ITP therapies. Danazol was found to be a potential therapeutic alternative to splenectomy in elderly ITP patients.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Idiopathic thrombocytopenic purpura (ITP) is often diagnosed in the elderly, but no specific guidelines exist for such patients. We describe our experience with ITP management in elderly patients and analyze the therapeutic response. METHODS: We retrospectively reviewed a cohort of 47 c...See full text at original site
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引用元：
https://doi.org/10.1016/j.ejim.2007.07.006

データ提供：米国国立医学図書館（NLM）

Idiopathic Thrombocytopenic Purpura in the Elderly

This study focuses on idiopathic thrombocytopenic purpura (ITP), an autoimmune disorder characterized by low platelet counts, in elderly patients. The researchers analyzed a cohort of 47 elderly ITP patients, evaluating their clinical characteristics, treatment responses, and side effects. They found that age influenced the presentation, response, and adverse effects of conventional ITP therapies, highlighting the need for tailored treatment approaches in this population.

Navigating the Challenges of ITP in the Elderly

The study's findings underscore the importance of understanding the unique challenges faced by elderly patients with ITP. The researchers explored potential alternative therapies, such as danazol, which might provide a viable option for some patients. The study underscores the need for further research to optimize ITP management in older adults.

Understanding and Managing ITP

ITP can be a challenging condition, and it's crucial to seek medical attention if you experience unusual bleeding or bruising. This study highlights the importance of tailoring treatment strategies to individual needs, particularly for elderly patients. Early diagnosis and appropriate management can significantly improve outcomes.

Dr.Camel's Conclusion

The journey through life is often accompanied by unexpected twists and turns, just like the unpredictable winds that sweep across the desert. This study sheds light on the complexities of ITP in the elderly, reminding us that age can significantly influence the course of this disease. It emphasizes the importance of tailored treatment approaches and ongoing research to improve patient care.
Date :
  1. Date Completed 2009-02-03
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

18848179

DOI: Digital Object Identifier

10.1016/j.ejim.2007.07.006

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Article Analysis
・Side Effects of danazol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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