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Costs of intermittent versus continuous antiretroviral therapy in patients with controlled HIV infection: a substudy of the ANRS 106 Window Trial.

Author: , AboulkerJean Pierre, BoyerLaurence, CharreauIsabelle, Durand-ZaleskiIsabelle, JeanblancGrégoire, MarchouBruno, MolinaJean Michel, SaouzanetMarine, TangrePhilippe

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This cost study analyzed the impact of an intermittent treatment (IT) strategy compared to continuous treatment (CT) in HIV-1 infected adults receiving highly active antiretroviral therapy (HAART). Four hundred three patients were randomized to either IT or CT. While the primary endpoint (proportion of patients with CD4 cell count below 300 cells per microliter) was not significantly different between groups, IT resulted in a 40% reduction in HAART medication costs without increasing costs related to adverse events or consultations.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Structured treatment interruptions in chronic HIV infection have been explored as a drug-sparing strategy to reduce drug-related adverse events and costs while maintaining CD4 cell counts at a level high enough to prevent the risk of disease progression. OBJECTIVES: To test the hypothes...See full text at original site
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引用元：
https://doi.org/10.1097/QAI.0b013e31818a657c

データ提供：米国国立医学図書館（NLM）

Intermittent vs. Continuous Antiretroviral Therapy: A Cost-Effective Oasis

HIV/AIDS research explores strategies for managing the virus and improving the quality of life of patients. This cost study analysis, conducted within the context of a randomized open-label trial, compares the cost-effectiveness of intermittent versus continuous antiretroviral therapy (ART) in patients with controlled HIV infection. The authors analyzed cost data from 391 patients and found that intermittent ART resulted in a significant reduction in total medical costs, primarily due to lower ART medication costs, without compromising the effectiveness of treatment.

A New Path in the Sands: Intermittent ART for HIV Management

The study's findings suggest that intermittent ART may offer a cost-effective approach to managing HIV infection while maintaining viral suppression.

Navigating the Desert of HIV/AIDS

As a researcher working in the field of HIV/AIDS, I am always looking for ways to improve the accessibility and affordability of treatment. This study provides valuable insight into the potential cost savings of intermittent ART.

Dr. Camel's Conclusion

This cost study analysis, conducted within the context of a randomized open-label trial, compares the cost-effectiveness of intermittent versus continuous antiretroviral therapy (ART) in patients with controlled HIV infection. The authors analyzed cost data from 391 patients and found that intermittent ART resulted in a significant reduction in total medical costs, primarily due to lower ART medication costs, without compromising the effectiveness of treatment.

Date :
  1. Date Completed 2009-02-19
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

18931625

DOI: Digital Object Identifier

10.1097/QAI.0b013e31818a657c

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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