Paper Details

  1. Home
  2. Paper Details

Efficacy and safety of sodium hyaluronate in the treatment of Wilkes stage II disease.

Author: Gutierrez-PerezJose-Luis, Hernandez-PachecoEsther, Infante-CossioPedro, Oliveras-MorenoJose-Maria, Oliveras-QuintanaTeresa

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This randomized controlled trial compared intra-articular (IA) infiltration of sodium hyaluronate (SH) with oral methocarbamol-paracetamol for treatment of temporomandibular joint (TMJ) pain in patients with Wilkes stage II disease. The SH group demonstrated significantly reduced pain at rest, pain on jaw opening, and pain on mastication compared to the control group. TMJ function was also significantly improved in the SH group. No adverse reactions were detected with SH.
Paper Details　
Original Abstract of the Article :
PURPOSE: To show whether an intra-articular (IA) infiltration of 1 mL sodium hyaluronate (SH) into the temporomandibular joint (TMJ) would significantly reduce pain and improve joint function in Wilkes stage II disease, compared with the oral administration of a combination of methocarbamol and para...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.joms.2008.01.067

データ提供：米国国立医学図書館（NLM）

Seeking Relief in the Shifting Sands of TMJ Pain

Temporomandibular joint (TMJ) disorders can feel like an endless desert, with persistent pain and limited jaw movement. This research explores the potential of intra-articular (IA) sodium hyaluronate (SH) infiltration as a treatment for Wilkes stage II TMJ disease. Researchers compared the effects of SH injection to oral administration of methocarbamol and paracetamol in patients with this condition. The study found that SH injection resulted in significant pain reduction and improved joint function compared to the control group. This is akin to finding a cool oasis amidst the scorching desert, offering much-needed respite and relief from the discomfort.

A Promising Oasis in the Desert of TMJ Pain

The study's findings highlight the potential of SH infiltration as a promising treatment option for Wilkes stage II TMJ disease. The SH group experienced statistically significant pain relief and improved joint function compared to the control group. This suggests a potential shift in the sands of TMJ treatment, moving towards more targeted and effective therapies. Imagine a desert traveler stumbling upon a lush oasis; the SH injection provides a similar sense of relief and restoration, offering a renewed path to mobility and comfort.

Finding Relief in the Desert

The research suggests that SH infiltration could be a valuable tool in the treatment of Wilkes stage II TMJ disease, offering hope for individuals suffering from this debilitating condition. Further research is needed to fully understand the long-term effects and optimal application of this treatment approach. Just as desert travelers must learn to navigate the ever-changing terrain, healthcare professionals must continue to explore and refine treatment options to address the specific needs of each patient.

Dr. Camel's Conclusion

This study provides a ray of hope for patients with Wilkes stage II TMJ disease, suggesting that SH infiltration, like a refreshing oasis, could offer significant pain relief and improved joint function.
Date :
  1. Date Completed 2008-11-03
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

18940487

DOI: Digital Object Identifier

10.1016/j.joms.2008.01.067

Related Literature

Article Analysis
・Side Effects of methocarbamol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.