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Subthalamic nucleus stimulation in severe obsessive-compulsive disorder.

Author: , AgidYves, AouizerateBruno, ArbusChristophe, ArdouinClaire, BardinetEric, BatailleBenoit, BaupNicolas, BenabidAlim-Louis, BougerolThierry, BurbaudPierre, ChabardèsStephan, ChaynesPatrick, ChéreauIsabelle, CornuPhilippe, CzerneckiVirginie, DamierPhilippe, DerostPhilippe, DevauxBertrand, DormontDidier, FontaineDenys, HouetoJean-Luc, JaafariNematollah, KrackPaul, KrebsMarie-Odile, MalletLuc, MatteiVianney, MilletBruno, PelissoloAntoine, PollakPierre, PolosanMircea, RaoulSylvie, VérinMarc, WelterMarie-Laure, YelnikJérôme, du MontcelSophie Tezenas

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Stimulation of the subthalamic nucleus may reduce the symptoms of severe forms of OCD but is associated with a substantial risk of serious adverse events, including intracerebral hemorrhage and infections.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Severe, refractory obsessive-compulsive disorder (OCD) is a disabling condition. Stimulation of the subthalamic nucleus, a procedure that is already validated for the treatment of movement disorders, has been proposed as a therapeutic option. METHODS: In this 10-month, crossover, double...See full text at original site
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引用元：
https://doi.org/10.1056/NEJMoa0708514

データ提供：米国国立医学図書館（NLM）

Subthalamic Nucleus Stimulation for Obsessive-Compulsive Disorder: Exploring New Frontiers in Brain Stimulation

Obsessive-compulsive disorder (OCD) is a debilitating condition, like a persistent sandstorm that can cloud our thoughts and actions. This study investigates the potential of subthalamic nucleus stimulation, a technique already used to treat movement disorders, as a therapeutic option for severe, refractory OCD. It's like a journey through the desert of the brain, seeking new pathways to alleviate the suffering caused by OCD.

A Glimpse into the Future of OCD Treatment: The Promise of Brain Stimulation

The study's findings suggest that subthalamic nucleus stimulation may offer a potential avenue for relief from severe OCD, reducing symptoms and improving quality of life. This is a significant development, offering a beacon of hope for those who have struggled to find effective treatments. It's like discovering a hidden oasis in the desert of OCD, providing a potential source of respite and healing.

Navigating the Complexities of Brain Stimulation: Cautious Optimism and Continued Research

While the study's results are promising, it's essential to acknowledge the significant risks associated with brain stimulation. It's like traversing a treacherous desert landscape, where navigating the terrain requires careful planning and awareness of potential hazards. Continued research is vital to optimize the safety and efficacy of this technique, ensuring that it can truly benefit those who need it most.

Dr.Camel's Conclusion

This study offers a glimpse into the future of OCD treatment, exploring the potential of brain stimulation to alleviate severe symptoms. It's a reminder that the desert of medical research is vast and ever-expanding, with new possibilities constantly emerging. By embracing innovative approaches and prioritizing patient safety, we can continue to advance our understanding of brain disorders and develop more effective treatments.

Date :
  1. Date Completed 2008-11-24
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

19005196

DOI: Digital Object Identifier

10.1056/NEJMoa0708514

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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