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Somatosensory evoked potentials as indicators of altered cerebral excitability during psychotropic drug treatment.

Author: FörstlH, Pohlmann-EdenB, ZagorskiA

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Overview

Increased amplitude of the early cortical somatosensory evoked potentials was observed in five patients who developed myoclonus and/or generalized seizures during treatment with antidepressants, returning to normal values after discontinuation of the drugs.
Paper Details　
Original Abstract of the Article :
We observed an increase in the amplitude of the early cortical somatosensory evoked potentials (SSEPs) in five patients who developed myoclonus and/or generalized seizures during treatment with antidepressants. The increases correlated closely with the course of the clinical disturbances. In every c...See full text at original site
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引用元：
https://doi.org/10.1016/0006-3223(91)90226-c

データ提供：米国国立医学図書館（NLM）

Somatosensory Evoked Potentials: A Window into Altered Cerebral Excitability

The field of neurology explores the intricate workings of the brain and its susceptibility to various conditions. This research investigates the potential of somatosensory evoked potentials (SSEPs) as indicators of altered brain excitability during psychotropic drug treatment. The study observed an increase in SSEP amplitude in patients who experienced myoclonus or seizures while taking antidepressants, suggesting a correlation between SSEP changes and increased risk of adverse effects. These findings highlight the potential for SSEPs to monitor patients at risk and provide valuable insights into drug-induced neurological changes.

SSEPs: A Potential Tool for Monitoring Psychotropic Drug Treatment

The study demonstrates the potential of SSEPs as a tool for monitoring patients undergoing psychotropic drug treatment. The correlation between increased SSEP amplitude and adverse neurological events suggests that SSEPs could be used to identify individuals at an elevated risk of these complications. This information could be valuable for adjusting treatment plans and ensuring patient safety.

Understanding the Impact of Psychotropic Drugs on the Brain

Psychotropic drugs can have a profound impact on brain function. Understanding the potential side effects and monitoring for any changes in neurological activity is crucial for ensuring patient safety. Consulting a healthcare professional regarding any concerns about psychotropic drug treatment is vital for receiving appropriate care and minimizing risks.

Dr.Camel's Conclusion

The brain is a complex and delicate organ, much like a delicate oasis in the desert. By studying the subtle changes in brain activity, such as those revealed by SSEPs, we can better understand the impact of medications and ensure the safe and effective treatment of neurological conditions.

Date :
  1. Date Completed 1991-07-03
  2. Date Revised 2019-08-15
Further Info :

Pubmed ID

1903661

DOI: Digital Object Identifier

10.1016/0006-3223(91)90226-c

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