Comparison of the conjunctival toxicity of topical ocular antiallergic agents.

Author: KimNami, LeeJi Eun, LeeJong Soo, OumBoo Sup

Paper Details 
Original Abstract of the Article :
PURPOSE: The aim of this study was to investigate the cytotoxic effect of topical ocular allergic agents with H1-receptor antagonism and inhibition of histamine release from mast cells on the cultured conjunctival cells of rabbit in vitro. METHODS: Cell damage by the topical ocular antiallergic age...See full text at original site
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引用元:
https://doi.org/10.1089/jop.2008.0071

データ提供:米国国立医学図書館(NLM)

Topical Ocular Antiallergic Agents: Comparing Conjunctival Toxicity

The vast desert of allergic reactions can be a challenging terrain, and the eyes are often susceptible to these sensitivities. This study, focusing on the field of [ophthalmology], investigates the conjunctival toxicity of three topical ocular antiallergic agents: azelastine hydrochloride, ketotifen fumarate, and olopatadine hydrochloride. The researchers used an in vitro model to compare the cytotoxic effects of these agents on cultured rabbit conjunctival cells. The study found that all three agents induced some level of cell damage, but olopatadine hydrochloride was associated with significantly less toxicity compared to azelastine hydrochloride and ketotifen fumarate. The study highlights the importance of considering the potential conjunctival toxicity of topical ocular antiallergic agents when treating allergic conjunctivitis.

Olopatadine: A Less Toxic Option for Allergic Conjunctivitis

The study provides valuable information on the comparative conjunctival toxicity of topical ocular antiallergic agents. The [significantly lower toxicity of olopatadine hydrochloride] compared to the other two agents suggests that it may be a preferable treatment option for allergic conjunctivitis, particularly in patients with sensitive eyes. The study encourages clinicians to consider the potential toxicity of topical ocular antiallergic agents and to choose the most appropriate treatment based on individual patient needs.

Understanding Treatment Options

If you experience allergic conjunctivitis, it is important to consult with an ophthalmologist. They can diagnose the cause of your allergies and recommend the most appropriate treatment. Discuss your concerns about potential side effects, including conjunctival toxicity, with your healthcare provider. Remember that open communication and a proactive approach to managing allergies can help you maintain optimal eye health and well-being.

Dr.Camel's Conclusion

This study provides valuable insights into the comparative conjunctival toxicity of topical ocular antiallergic agents. The study's findings highlight the importance of considering the potential toxicity of these medications and of choosing the most appropriate treatment based on individual patient needs. As a wise camel, I encourage you to stay informed about the latest research and to prioritize your eye health.

Date :
  1. Date Completed 2009-03-11
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

19049267

DOI: Digital Object Identifier

10.1089/jop.2008.0071

Related Literature

SNS
PICO Info
in preparation
Languages

English

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