Are topical antimicrobials effective against bacteria that are highly resistant to systemic antibiotics?

Author: DurkeePaula, GallagherJames J, GardnerJason, GreenhalghDavid G, HerndonDavid N, KaganRichard J, NeelyAlice N, TompkinsRonald G, WardenGlenn D

Paper Details 
Original Abstract of the Article :
An increasing number of bacteria are resistant to multiple systemic antibiotics. The purpose of this study was to determine if topical antimicrobials are still effective against multi-drug resistant organisms (MDROs). MDROs, including Acinetobacter, Pseudomonas, Klebsiella, Staphylococcus, and Enter...See full text at original site
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引用元:
https://doi.org/10.1097/BCR.0b013e3181921eed

データ提供:米国国立医学図書館(NLM)

Topical Antimicrobials: A Vital Tool in the Fight Against Drug-Resistant Bacteria

This research explores the effectiveness of [topical antimicrobials] against [multi-drug resistant organisms (MDROs)] in the context of [burn infections]. The study investigated the sensitivity of MDROs to commonly used topical agents, comparing their effectiveness to non-MDROs. The researchers found that while many topicals remain effective against some MDROs, they are generally less effective than against non-MDROs, highlighting the challenges of combating drug-resistant infections.

Drug Resistance: An Ever-Evolving Threat

This study underscores the growing challenge of drug resistance in bacteria. The researchers found that MDROs are less susceptible to topical antimicrobials than their non-resistant counterparts. This research emphasizes the need for continued surveillance and development of new antimicrobial agents to combat the threat of drug resistance.

Managing Infections in the Age of Drug Resistance: A Multifaceted Approach

This research highlights the importance of a comprehensive approach to managing infections in the era of drug resistance. The study's findings underscore the need for judicious use of antimicrobials, infection control measures, and ongoing research to develop new therapeutic strategies. This research serves as a reminder that the battle against drug-resistant bacteria requires a collective effort involving clinicians, researchers, and policymakers.

Dr.Camel's Conclusion

This research sheds light on the complex and evolving landscape of antimicrobial resistance, highlighting the challenges of treating infections caused by MDROs. The study emphasizes the importance of a multi-faceted approach to infection control and the need for continued research and development of new antimicrobial agents to combat this growing threat.

Date :
  1. Date Completed 2009-03-06
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

19060725

DOI: Digital Object Identifier

10.1097/BCR.0b013e3181921eed

Related Literature

SNS
PICO Info
in preparation
Languages

English

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