Effect of raloxifene and low-dose percutaneous 17beta-estradiol on menopause symptoms and endometrium--a randomized controlled trial.

Author: CappEdison, EdelweissMaria Isabel, ValiatiBeatriz, WenderMaria Celeste Osório, de FreitasFernando Monteiro

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To investigate the effects on climacteric symptoms and endometrium of percutaneous low-dose 17beta-estradiol associated with raloxifene in postmenopausal women. DESIGN: randomized placebo-controlled study. METHOD: Fifty-two postmenopausal women with moderate to severe hot flushes were r...See full text at original site
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引用元:
https://doi.org/10.1016/j.maturitas.2008.10.013

データ提供:米国国立医学図書館(NLM)

Effect of raloxifene and low-dose percutaneous 17beta-estradiol on menopause symptoms and endometrium

The [Menopause] transition is a natural part of life for women, but it can bring a variety of challenges, including [Climacteric symptoms]. This study investigates the potential benefits of combining [Raloxifene] with [Percutaneous low-dose 17beta-estradiol] to alleviate [Menopause symptoms] while maintaining [Endometrial safety]. The researchers designed a randomized placebo-controlled study to assess the effectiveness of this approach. The findings shed light on the potential benefits of this treatment strategy in managing [Menopause symptoms] while mitigating potential risks to the [Endometrium].

Hormonal Harmony

The study found that [Raloxifene+E2] and [Placebo] were significantly superior to [Raloxifene] in reducing [Hot flush severity]. Furthermore, the combination therapy did not cause any significant changes in [Endometrial thickness] or lead to [Endometrial proliferation]. These results suggest that [Raloxifene+E2] may offer a safe and effective treatment option for managing [Menopause symptoms] in women concerned about [Endometrial health].

Navigating the Oasis of Menopause

This research provides valuable insights for women experiencing [Menopause] and seeking relief from [Climacteric symptoms]. It highlights the importance of [Considering different treatment options] and discussing potential risks and benefits with a healthcare professional. The study emphasizes the importance of [Personalized medicine] and the need for [Continued research] to further understand the effects of various treatments on [Menopause symptoms] and [Endometrial health].

Dr. Camel's Conclusion

Navigating the oasis of [Menopause] can be a journey of discovery. This research provides valuable insights into the potential benefits of [Hormone therapy] in managing [Menopause symptoms] while maintaining [Endometrial health]. It reminds us that [Each woman's experience is unique] and that finding the right path requires [Open communication with a healthcare professional].

Date :
  1. Date Completed 2009-04-14
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

19097715

DOI: Digital Object Identifier

10.1016/j.maturitas.2008.10.013

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English

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