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Difluprednate ophthalmic emulsion 0.05% for postoperative inflammation and pain.

Author: , CookeDavid L, CrockettRobert S, KorenfeldMichael S, SilversteinSteven M, VogelRoger

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Difluprednate given 2 or 4 times a day cleared postoperative inflammation and reduced pain rapidly and effectively. There were no serious ocular adverse events. Fewer adverse events were reported in the difluprednate-treated groups than in the placebo group.
Paper Details　
Original Abstract of the Article :
PURPOSE: To assess the efficacy and safety of difluprednate ophthalmic emulsion 0.05% (Durezol) 2 or 4 times a day compared with those of a placebo in the treatment of inflammation and pain associated with ocular surgery. SETTING: Twenty-six clinics in the United States. METHODS: One day after uni...See full text at original site
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引用元：
https://doi.org/10.1016/j.jcrs.2008.09.024

データ提供：米国国立医学図書館（NLM）

Difluprednate: A Safe and Effective Treatment for Postoperative Inflammation and Pain

Ocular surgery can often lead to inflammation and pain, which can significantly impact recovery. This study, published in the journal American Journal of Ophthalmology, investigates the efficacy and safety of difluprednate ophthalmic emulsion 0.05% (Durezol) in treating postoperative inflammation and pain after ocular surgery.

Difluprednate: Reducing Inflammation and Pain

The study found that difluprednate, administered twice or four times daily, effectively reduced postoperative inflammation and pain compared to placebo. The treatment was well-tolerated, with few serious ocular adverse events. This research highlights the potential of difluprednate as a safe and effective option for managing postoperative inflammation and pain after ocular surgery.

Optimizing Postoperative Care

This study provides valuable insights for ophthalmologists seeking effective treatments for postoperative inflammation and pain. By providing a safe and effective option for managing these common side effects, difluprednate can contribute to a smoother recovery process for patients undergoing ocular surgery. This research emphasizes the importance of continuous advancements in treatment options to improve patient care and outcomes.

Dr.Camel's Conclusion

Ocular surgery can be a delicate procedure, and managing postoperative inflammation and pain is crucial for a comfortable recovery. This study demonstrates the effectiveness of difluprednate in providing relief from these common side effects. It's a testament to the ongoing efforts to improve postoperative care and enhance patient well-being.

Date :
  1. Date Completed 2009-03-05
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

19101421

DOI: Digital Object Identifier

10.1016/j.jcrs.2008.09.024

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・Effects of difluprednate ophthalmic
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PICO Info
in preparation
Languages

English

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