Paper Details

  1. Home
  2. Paper Details

Select comorbid personality disorders and the treatment of chronic depression with nefazodone, targeted psychotherapy, or their combination.

Author: ArnowBruce A, BlalockJanice A, KeitnerGabor I, KleinDaniel N, MadduxRachel E, ManberRachel, MarkowitzJohn C, RisoLawrence P, RothbaumBarbara O, ThaseMichael E

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Comorbid Axis II disorders did not negatively affect treatment outcome and did not differentially affect response to psychotherapy versus medication.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Individuals with chronic depression respond poorly to both medication and psychotherapy. The reasons for the poorer response, however, remain unclear. One potential factor is the presence of comorbid Axis II personality disorders (PDs), which occur at high rates among these patients. ME...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.jad.2009.01.010

データ提供：米国国立医学図書館（NLM）

Chronic Depression: Navigating the Desert of Comorbid Personality Disorders

Chronic depression is a challenging condition to treat, and the presence of comorbid personality disorders can further complicate the therapeutic process. This study, published in Journal of Affective Disorders, examines the impact of comorbid personality disorders on the effectiveness of nefazodone (a medication) and targeted psychotherapy for chronic depression. The researchers found that the presence of comorbid personality disorders did not negatively affect treatment outcome, suggesting that treatment approaches may not need to be significantly altered for patients with these co-occurring conditions.

Chronic Depression: A Complex Landscape

The study highlights the complex interplay between depression and personality disorders. While these conditions can sometimes coexist, they do not necessarily interfere with the effectiveness of treatment. The researchers suggest that patients with comorbid personality disorders may benefit from the same treatment approaches as those without these conditions, emphasizing the importance of individualized care and a comprehensive approach to treatment.

Chronic Depression: A Call for Understanding

This study underscores the importance of recognizing the nuances of mental health conditions and tailoring treatment approaches accordingly. It's a reminder that the desert of mental health is vast and diverse, with each patient presenting unique challenges. By understanding the complexities of these conditions, we can provide more effective and compassionate care to those in need.

Dr.Camel's Conclusion

This research provides valuable insights into the treatment of chronic depression in the presence of comorbid personality disorders. It suggests that a comprehensive and individualized approach to treatment can be effective, even for patients with complex mental health conditions. Remember, the journey through mental health challenges is unique to each individual, and a compassionate and understanding approach can make a significant difference in the healing process.

Date :
  1. Date Completed 2009-11-30
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19217168

DOI: Digital Object Identifier

10.1016/j.jad.2009.01.010

Related Literature

Article Analysis
・Effective treatment of personality disorders
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.