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Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins.

Author: GreenbergL, RavnikarV, RosnerB, SacksF M, SchiffI, WalshB W

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Postmenopausal estrogen-replacement therapy may reduce the risk of cardiovascular disease by favorably altering plasma lipid levels. However, the precise effects of low-dose estrogens on lipoproteins and their mechanism are unknown.
Paper Details　
Original Abstract of the Article :
Postmenopausal estrogen-replacement therapy may reduce the risk of cardiovascular disease, and this beneficial effect may be mediated in part by favorable changes in plasma lipid levels. However, the effects on plasma lipoprotein levels of postmenopausal estrogens in the low doses currently used hav...See full text at original site
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引用元：
https://doi.org/10.1056/NEJM199110243251702

データ提供：米国国立医学図書館（NLM）

Estrogen Replacement and Lipoproteins: A Balancing Act in the Desert of Hormones

The field of [hormonal health] is a complex landscape, with intricate interactions between various hormones and their effects on different systems. This study explores the effects of [postmenopausal estrogen replacement therapy] on [plasma lipoprotein levels]. Imagine a camel navigating a desert, seeking balance and sustenance in a harsh environment. Estrogen replacement therapy, in this analogy, can be seen as a way to restore balance to the hormonal landscape, potentially influencing various aspects of health, including lipid metabolism.

Estrogen Replacement: A Balancing Act in the Desert of Lipids

The study found that [postmenopausal estrogen replacement therapy] can [alter plasma lipoprotein levels], potentially contributing to the beneficial effects observed in cardiovascular health. This highlights the intricate interplay between hormones and lipid metabolism. The study’s findings underscore the importance of [individualized treatment approaches] when considering estrogen replacement therapy, as the effects on lipid levels may vary depending on factors such as dosage and individual characteristics.

Navigating the Desert of Hormones: Seeking Balance and Wellness

This study emphasizes the importance of understanding the complex interactions between hormones and lipid metabolism. By carefully evaluating the potential benefits and risks associated with estrogen replacement therapy, individuals can make informed decisions about their health and well-being. It is crucial to work with a healthcare professional to determine the best course of treatment for your specific needs and to monitor for any potential side effects.

Dr. Camel's Conclusion

This study highlights the complex relationship between estrogen replacement therapy and plasma lipoprotein levels. It serves as a reminder that individual responses to hormonal treatments can vary, and it is essential to approach these therapies with careful consideration and informed decision-making. The findings emphasize the importance of personalized care and close monitoring to ensure optimal outcomes.

Date :
  1. Date Completed 1991-10-29
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

1922206

DOI: Digital Object Identifier

10.1056/NEJM199110243251702

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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