[Postoperative analgesia with fentanyl combined with flurbiprofen axetil following gynecologic surgery for turnor].

Author: BaiXiao-hui, CaoLong-hui, LinWen-qian, WenLi-li, ZhongZhong-jian

Paper Details 
Original Abstract of the Article :
OBJECTIVE: a To observe the analgesic effect of fentanyl combined with flurbiprofen axetil for postoperative analgesia after gynecologic surgery. METHODS: One hundred and forty patients undergoing gynecologic surgery were randomized equally into two groups to receive postoperative patient controlle...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19246310

データ提供:米国国立医学図書館(NLM)

Pain Relief After Gynecologic Surgery: Fentanyl and Flurbiprofen Axetil

In the field of post-operative pain management, researchers are constantly seeking ways to improve pain relief while minimizing side effects. This study delves into the effectiveness of combining fentanyl and flurbiprofen axetil for pain relief after gynecologic surgery. The authors employed a randomized, controlled trial to compare the analgesic effects of fentanyl alone and fentanyl combined with flurbiprofen axetil, delivered via patient-controlled intravenous analgesia (PCIA). The findings reveal that the combination therapy significantly reduced the dosage of fentanyl required while achieving comparable pain relief. Moreover, the study observed a lower incidence of adverse effects, such as nausea, dizziness, and lethargy, in the group receiving the combination therapy. These results suggest that combining fentanyl with flurbiprofen axetil may offer a more effective and well-tolerated approach to managing post-operative pain after gynecologic surgery.

Combination Therapy Shows Promise for Post-Operative Pain

The study demonstrated that combining fentanyl with flurbiprofen axetil resulted in a significant reduction in fentanyl dosage (P<0.05) while maintaining comparable pain relief, as measured by the Prine-Henry score (PHS), at the 6-hour and 12-hour time points. This finding is encouraging as it implies that a lower dose of fentanyl might lead to fewer adverse effects. The authors noted that the combination therapy significantly reduced the incidence of adverse effects associated with fentanyl, including nausea, dizziness, and lethargy.

Minimizing Side Effects While Managing Pain

This study underscores the potential of combining fentanyl with flurbiprofen axetil as a safer and more effective strategy for post-operative pain management. By reducing the required fentanyl dosage, the authors believe that the combination therapy may lead to fewer side effects, potentially improving the overall patient experience after gynecologic surgery. The study findings warrant further investigation to confirm these benefits and explore the long-term implications for patient recovery and well-being.

Dr.Camel's Conclusion

This research sheds light on the potential of combining fentanyl with flurbiprofen axetil to improve post-operative pain management. Just as a camel adapts to the harsh desert environment, this combination therapy may help patients better adapt to the challenges of post-operative pain. The findings suggest a path towards more effective and tolerable pain management strategies in gynecologic surgery, which is definitely good news for patients and surgeons alike.

Date :
  1. Date Completed 2010-04-29
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

19246310

DOI: Digital Object Identifier

19246310

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Languages

Chinese

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