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Randomized study comparing the efficacy and tolerance of a lipophillic hydroxy acid derivative of salicylic acid and 5% benzoyl peroxide in the treatment of facial acne vulgaris.

Author: BissonnetteR, BolducC, MaariC, NigenS, ProvostN, RougierA, SeitéS

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A lipophillic derivative of salicylic acid (LHA) was as effective as 5% benzoyl peroxide in reducing both inflammatory and non-inflammatory lesions in patients with mild to moderate acne vulgaris. LHA may be a suitable treatment option for patients intolerant to benzoyl peroxide.
Paper Details　
Original Abstract of the Article :
BACKGROUND: New topical treatments for acne vulgaris are needed for patients who have tolerance problems with current treatments. AIMS: To compare the efficacy and tolerance of a lipophillic derivative of salicylic acid (lipo hydroxy acid or LHA) containing formulation and 5% benzoyl peroxide in su...See full text at original site
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引用元：
https://doi.org/10.1111/j.1473-2165.2009.00418.x

データ提供：米国国立医学図書館（NLM）

Comparing Lipophilic Hydroxy Acid Derivative of Salicylic Acid and Benzoyl Peroxide for Acne Treatment

The field of [Dermatology] is continually searching for [safe and effective treatments] for [acne vulgaris]. This research compares the [efficacy and tolerability] of a [lipophilic derivative of salicylic acid (LHA)] formulation to [5% benzoyl peroxide] in patients with [mild to moderate acne vulgaris]. The authors conducted a [randomized, double-blind, controlled trial] to evaluate the [clinical outcomes] of both treatments over a [12-week period]. Their findings suggest that [both LHA and benzoyl peroxide were effective in reducing acne lesions] with no significant difference in efficacy between the two treatments.

LHA: A Potential Alternative for Benzoyl Peroxide-Intolerant Patients

This research offers a potential alternative treatment option for patients with [acne vulgaris] who experience [intolerance to benzoyl peroxide]. The [LHA formulation] demonstrated comparable efficacy to [benzoyl peroxide] while potentially offering a [better tolerability profile]. This finding is particularly important for patients who struggle with [skin irritation, dryness, or redness] associated with [benzoyl peroxide] treatment.

Navigating Acne Treatment Options

It is essential to [consult with a dermatologist] to determine the most appropriate treatment for your acne. The choice of treatment depends on various factors, including [the severity of acne, your skin type, and your individual tolerance to different medications]. It is important to remember that [consistent and long-term treatment] is crucial for achieving optimal results and maintaining clear skin.

Dr.Camel's Conclusion

Just as a camel can adapt to different environments, this study shows that LHA can potentially be a viable alternative to benzoyl peroxide for patients with acne. This might be a good option for those who are sensitive to benzoyl peroxide, offering a smoother journey towards clear skin.

Date :
  1. Date Completed 2009-06-16
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

19250161

DOI: Digital Object Identifier

10.1111/j.1473-2165.2009.00418.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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