[High-dose trospium chloride in therapy of detrusor hyperreflexia].

Author: GiannettiB M, MadersbacherH, MürtzG, RichterR, StöhrerM

Paper Details 
Original Abstract of the Article :
The efficacy and tolerance of a high-dose treatment with trospium chloride (20 mg twice daily) were investigated in pilot studies carried out in three trial centres and involving a total of 29 patients suffering from reflex bladder due to transverse lesions of the spinal cord with paraplegia. In all...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1926674

データ提供:米国国立医学図書館(NLM)

High-Dose Trospium Chloride: A Potential Treatment for Detrusor Hyperreflexia

This study explores the field of urology, focusing on the effectiveness of high-dose trospium chloride in treating detrusor hyperreflexia, a condition characterized by involuntary bladder contractions. Researchers conducted pilot studies involving 29 patients with reflex bladder due to spinal cord lesions, evaluating the efficacy and tolerance of high-dose trospium chloride (20 mg twice daily) in improving bladder function.

High-Dose Trospium Chloride: Improved Bladder Function and Tolerability

The researchers found that high-dose trospium chloride significantly improved bladder function in the majority of patients. There was a clear increase in maximum bladder capacity, a marked decrease in maximum detrusor pressure, and an increase in bladder compliance, leading to a reduction in urinary frequency. The treatment also effectively controlled urinary incontinence caused by detrusor hyperreflexia, improving urinary continence. The researchers concluded that high-dose trospium chloride was well-tolerated and effective in managing detrusor hyperreflexia in patients with spinal cord lesions.

Managing Bladder Issues: Exploring Treatment Options

This research offers promising insights into the potential of high-dose trospium chloride for treating detrusor hyperreflexia. The findings highlight the importance of personalized treatment approaches for managing bladder dysfunction. Individuals experiencing bladder problems should consult with a healthcare professional to discuss appropriate diagnostic and treatment options.

Dr.Camel's Conclusion

Just as a camel navigates the desert, finding the right way to manage bladder issues can be a journey. This research sheds light on the potential of high-dose trospium chloride for improving bladder function in individuals with detrusor hyperreflexia, offering hope for a more comfortable and fulfilling life.

Date :
  1. Date Completed 1991-11-20
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1926674

DOI: Digital Object Identifier

1926674

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PICO Info
in preparation
Languages

German

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