Comparison of intravesical botulinum toxin type A injections plus hydrodistention with hydrodistention alone for the treatment of refractory interstitial cystitis/painful bladder syndrome.

Author: ChancellorMichael B, KuoHann-Chorng

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare the clinical effectiveness of botulinum toxin type A (BoNT-A) injections followed by hydrodistention (HD) with HD alone in patients with interstitial cystitis/painful bladder syndrome (IC/PBS). PATIENTS AND METHODS: A prospective, randomized study was performed in a urological...See full text at original site
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引用元:
https://doi.org/10.1111/j.1464-410X.2009.08495.x

データ提供:米国国立医学図書館(NLM)

Botulinum Toxin for Interstitial Cystitis: A Promising Treatment

Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic condition characterized by debilitating bladder pain. This research explores the potential of intravesical botulinum toxin type A (BoNT-A) injections, combined with hydrodistention (HD), as a treatment option for refractory IC/PBS. The authors conducted a prospective, randomized study comparing BoNT-A injections followed by HD to HD alone in patients who had not responded to conventional therapies. This study provides compelling evidence that BoNT-A injections may offer a more effective treatment approach for refractory IC/PBS.

BoNT-A Injections Show Superior Results for Refractory IC/PBS

The study demonstrated that BoNT-A injections followed by HD significantly improved clinical outcomes compared to HD alone in patients with refractory IC/PBS. The BoNT-A group showed greater reductions in bladder pain, increased functional bladder capacity, and sustained symptom improvement over time. These findings suggest that BoNT-A injections may be a valuable therapeutic option for patients with refractory IC/PBS.

Exploring New Treatments for Chronic Bladder Pain

This research highlights the potential of BoNT-A injections as a promising treatment for IC/PBS, particularly for those who have not responded to conventional therapies. The study underscores the importance of exploring novel treatments for chronic bladder pain and offers hope for individuals struggling with this debilitating condition. The findings encourage further research to optimize the use of BoNT-A in IC/PBS treatment.

Dr.Camel's Conclusion

Imagine a camel enduring the relentless burning sands of the desert, feeling the scorching pain of thirst. This research is like a cool, refreshing spring in the desert, offering a potential source of relief for those suffering from the pain of IC/PBS. BoNT-A injections offer a glimmer of hope, reminding us that the quest for effective treatments for chronic conditions is a constant pursuit.

Date :
  1. Date Completed 2009-09-28
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

19338543

DOI: Digital Object Identifier

10.1111/j.1464-410X.2009.08495.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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