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Control of esophageal and intragastric pH with compounded and manufactured omeprazole in patients with reflux esophagitis: a pilot study.

Author: BelarminoK, BritoEliza M, CarvalhoEmanuella B, CoelhoLuiz G, FrancoJunia D, MoretzsohnLuciana D, SoaresMarcela P

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study found that different omeprazole formulations, both compounded and manufactured, had similar effects on gastric acid secretion and esophageal acid exposure in patients with reflux esophagitis.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Proton pump inhibitors (PPI) are the drugs of choice for treatment of gastroesophageal reflux disease (GERD). Omeprazole, the first PPI commercialized, is now available in different formulations. OBJECTIVES: To compare the efficacy of different omeprazole formulations on gastric acid se...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/19383986

データ提供：米国国立医学図書館（NLM）

Omeprazole: A Tale of Two Formulations

This research dives into the intricate world of [proton pump inhibitors (PPIs)], the go-to treatment for [gastroesophageal reflux disease (GERD)]. Imagine GERD as a relentless desert wind, constantly blowing acid back up your esophagus. The authors conducted a pilot study to compare the efficacy of different [omeprazole] formulations on [gastric acid secretion] in patients with [GERD]. Their aim was to assess whether compounded and manufactured omeprazole formulations differed in their ability to control acid production.

Omeprazole: A Desert Oasis for Acid Reflux?

This pilot study found that both compounded and manufactured [omeprazole] formulations were effective in controlling [gastric acid secretion] in patients with [GERD]. While the study observed no significant difference between the formulations, it highlights the importance of considering different treatment options based on individual patient needs and preferences. This study, though limited in scope, offers valuable insights into the potential benefits of [omeprazole] for managing [GERD].

Managing Acid Reflux: A Desert Oasis of Knowledge

This study underscores the importance of [proton pump inhibitors (PPIs)] in treating [gastroesophageal reflux disease (GERD)]. It provides a reminder that there are different options available, and it's crucial to work with your doctor to determine the best approach for your individual needs. Remember, a healthy digestive system is like a well-maintained oasis, offering a haven of comfort and well-being.

Dr. Camel's Conclusion

This research is like a camel caravan navigating a desert of acid reflux. It explores the effectiveness of different [omeprazole] formulations, providing valuable insights for both patients and clinicians. Remember, managing [GERD] is a journey, and it's important to find a treatment strategy that suits your individual needs and preferences. Consult with your doctor to determine the best path towards relief from this common condition.
Date :
  1. Date Completed 2009-06-04
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

19383986

DOI: Digital Object Identifier

19383986

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・Effective treatment of gerd
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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