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Side effects of long-term oral antiviral therapy for hepatitis B.

Author: FontanaRobert J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Consensus Development Conference, NIHA conference organized by the NIH (National Institutes of Health) to develop consensus and recommendations on medical issues.

Overview

This review summarizes the safety profile of five approved oral nucleoside analogs used to treat chronic hepatitis B virus (HBV) infection, highlighting potential adverse effects, including mitochondrial toxicity, renal toxicity, and bone mineral density reduction.
Paper Details　
Original Abstract of the Article :
The aim of this review is to summarize the safety profile of the five approved oral nucleoside analogs used to treat chronic hepatitis B virus (HBV) infection, focusing on both the class adverse effects and those that have been reported with individual agents, as well as their safety in pregnancy. A...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1002/hep.22885

データ提供：米国国立医学図書館（NLM）

Navigating the Side Effects of Hepatitis B Treatment: A Desert of Challenges

The treatment of [chronic hepatitis B virus (HBV)] infection has undergone significant advancements, but managing the side effects of [oral nucleoside analogs] remains a crucial aspect of patient care. This review examines the safety profile of five approved oral nucleoside analogs, focusing on both class adverse effects and those associated with specific agents. The researchers highlight the importance of monitoring for potential [mitochondrial toxicity], [renal toxicity], and other side effects associated with these medications.

Side Effects: A Desert Oasis in Hepatitis B Treatment

The review emphasizes the importance of monitoring patients receiving these agents for potential side effects like [neuropathy], [myopathy], and [lactic acidosis]. It also highlights the need for careful monitoring of renal function in patients receiving [adefovir] and [tenofovir].

Managing Hepatitis B: A Desert Oasis in Treatment

This review provides valuable insights into the safety profile of oral nucleoside analogs used to treat chronic HBV infection. It underscores the importance of careful patient monitoring, early detection of potential side effects, and appropriate dose adjustments to optimize treatment outcomes.

Dr.Camel's Conclusion

This review is like a guide through the desert of hepatitis B treatment, offering guidance on navigating the potential side effects of nucleoside analogs. It reminds us of the importance of careful monitoring and a holistic approach to patient care.

Date :
  1. Date Completed 2009-06-03
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

19399802

DOI: Digital Object Identifier

10.1002/hep.22885

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