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[The risk of fracture with taking alpha blockers for treating benign prostatic hyperplasia].
Author: ChoiNam Kyoung, JungSun Young, KimYe Jee, LeeJoongyub, OhSeung June, ParkByung Joo, SeongJong Mi
Original Abstract of the Article :
OBJECTIVES: We evaluated the risk of fracture associated with hypotension-related adverse drug reaction caused by taking alpha blockers to treat benign prostatic hyperplasia (BPH). METHODS: We used the Health Insurance Review and Assessment Service database from January 1st 2005 to June 30th 2006 f...See full text at original site
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引用元:
https://doi.org/10.3961/jpmph.2009.42.3.165
データ提供:米国国立医学図書館(NLM)
Alpha Blockers for Benign Prostatic Hyperplasia: A Potential Risk of Fracture
Alpha blockers are commonly prescribed medications for treating benign prostatic hyperplasia (BPH), a condition that affects the prostate gland. This research investigated the potential association between alpha blocker use and the risk of fracture in elderly male patients with BPH. The authors analyzed a large healthcare database to assess the risk of fracture associated with different alpha blockers.
Risk of Fracture: A Potential Side-Effect of Alpha Blockers
The study found that doxazosin and tamsulosin were associated with an increased risk of fracture, while terazosin, at lower doses, showed a protective effect. This suggests that the risk of fracture may be influenced by the specific alpha blocker used and the dosage administered. The authors emphasize the importance of carefully considering the potential risks and benefits of alpha blocker therapy in elderly patients with BPH.
Navigating the Desert of Prostate Health: A Balanced Approach
This research highlights the importance of careful monitoring and risk assessment when prescribing alpha blockers for BPH, particularly in elderly patients who are at higher risk for falls and fractures. Healthcare providers should discuss the potential risks and benefits of alpha blocker therapy with their patients, considering individual factors such as age, comorbidities, and medication history.
Dr.Camel's Conclusion
This study highlights the potential for alpha blockers to increase the risk of fracture in elderly patients with BPH. Careful consideration of patient factors, including age, comorbidities, and concomitant medications, is essential when prescribing these medications to minimize potential risks and ensure patient safety.
Date :
- Date Completed 2009-08-25
- Date Revised 2013-11-21
Further Info :
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