Quetiapine augments the effect of citalopram in non-refractory obsessive-compulsive disorder: a randomized, double-blind, placebo-controlled study of 76 patients.

Author: DenysDamiaan, FluitmanSjoerd B A H A, MeinardiJantien C M, VulinkNienke C C, WestenbergHerman G M

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To assess the efficacy of quetiapine addition to citalopram in treatment-naive or medication-free obsessive-compulsive disorder (OCD) patients. METHOD: Seventy-six patients who met DSM-IV criteria for OCD and who were drug-free or drug-naive at entry were randomly assigned in a 10-week, ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.4088/JCP.08m04269

データ提供:米国国立医学図書館(NLM)

Quetiapine: A Potential Booster for Citalopram in Treating Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) presents a significant challenge for patients and clinicians alike. This study explores the potential for quetiapine, an antipsychotic medication, to augment the effectiveness of citalopram, a commonly prescribed antidepressant, in the treatment of OCD. The study meticulously designed a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of quetiapine in combination with citalopram for patients with treatment-naive or medication-free OCD. The results demonstrate the significant benefit of adding quetiapine to citalopram in reducing OCD symptoms, suggesting a potential new therapeutic strategy for managing this debilitating disorder.

Quetiapine's Boost for OCD Treatment: A New Path to Relief

This research provides compelling evidence for the potential of quetiapine to enhance the efficacy of citalopram in treating OCD. The study's findings indicate a significant improvement in OCD symptoms when quetiapine is combined with citalopram. This suggests a promising new approach for managing OCD, offering hope for patients who have not responded well to traditional treatments. Think of it like a camel finding a hidden spring of fresh water in a parched desert – a welcome source of relief and revitalization.

A Dual Approach to OCD Treatment: Combining Medications for Better Outcomes

This study suggests that combining quetiapine with citalopram may offer a more effective treatment strategy for OCD. This research highlights the potential benefits of a multimodal approach to managing complex mental health conditions, suggesting that a combination of therapies may be more effective than a single-pronged approach. It's like a camel relying on its hump for sustenance and its feet for navigating treacherous terrain – each element contributing to its overall success.

Dr.Camel's Conclusion

This research offers a potential breakthrough in the treatment of OCD, demonstrating the effectiveness of combining quetiapine with citalopram. This study reinforces the importance of exploring new therapeutic approaches for managing complex mental health conditions, offering hope for patients seeking relief. It's like finding a new oasis in a vast desert, offering a beacon of hope for those seeking a cure for their ailments. This research emphasizes the need for continued exploration and innovation in the field of mental health treatment.

Date :
  1. Date Completed 2009-08-11
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

19497245

DOI: Digital Object Identifier

10.4088/JCP.08m04269

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.