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The impact of proton-pump inhibitors on intraperitoneal sepsis: a word of caution for transgastric NOTES procedures.

Author: ChockAlana, CullenJohn, EasterDavid W, HorganSantiago, LeeJeffrey K, MintzYoav, MittalRavi, RamamoorthySonia L, SavuMichelle K, TalaminiMark A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the effects of proton-pump inhibitors (PPIs) on infection during transgastric natural orifice transluminal endoscopic surgery (NOTES). The study found that PPIs and alterations of gastric pH may have an effect on infection risk during transgastric surgery.
Paper Details　
Original Abstract of the Article :
During transgastric natural orifice transluminal endoscopic surgery (NOTES), there is an iatrogenic perforation of the gastric wall with leakage of gastric contents into the peritoneal cavity. The aim of this study is to determine the effect of proton-pump inhibitors (PPI) and alterations of gastric...See full text at original site
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引用元：
https://doi.org/10.1007/s00464-009-0559-3

データ提供：米国国立医学図書館（NLM）

Proton-Pump Inhibitors: A Word of Caution in the Desert of Transgastric NOTES

This study investigates the impact of [proton-pump inhibitors (PPIs)] on [intraperitoneal sepsis] during [transgastric natural orifice transluminal endoscopic surgery (NOTES)]. The authors emphasize the potential risks associated with PPIs in this context, highlighting the importance of considering their effects on gastric pH and the risk of infection. The researchers caution that PPIs may increase the risk of sepsis during transgastric NOTES, underscoring the need for careful consideration of their use in this surgical setting.

PPIs: A Hidden Danger in the Desert of NOTES Procedures

The study reveals a potential pitfall associated with the use of PPIs during transgastric NOTES procedures. The authors caution that PPIs may increase the risk of intraperitoneal sepsis, highlighting the importance of a cautious approach to their use in this surgical context. This is akin to discovering a hidden trap in a seemingly safe oasis, reminding us to be vigilant and aware of potential hazards.

Navigating the Desert of NOTES Procedures with Caution

This study emphasizes the need for a careful and informed approach to the use of PPIs during transgastric NOTES procedures. This is analogous to navigating a vast and challenging desert, where a thorough understanding of the terrain and potential risks is essential for a safe and successful journey. Clinicians must carefully consider the potential risks and benefits of PPI use in this context, prioritizing patient safety and minimizing the risk of complications.

Dr.Camel's Conclusion

This study highlights the potential risks associated with the use of PPIs during transgastric NOTES procedures, emphasizing the importance of a cautious approach to their use in this surgical setting. The researchers caution that PPIs may increase the risk of intraperitoneal sepsis, underscoring the need for careful consideration of their use and a thorough understanding of the potential complications.

Date :
  1. Date Completed 2010-04-08
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19551440

DOI: Digital Object Identifier

10.1007/s00464-009-0559-3

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Languages

English

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