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[Study on the efficacy and safety of short-term treatment including fluoroquinolones anti-tuberculosis drugs for rifampicin resistant pulmonary tuberculosis].
Author: ChuNai-hui, DuanmuHong-jin, KangWan-li, LiLiang, MiaoZi-ping, TanWei-guo, WangXiao-meng, XieYan-guang, YanXing-lu, YangYing-zhou, YouYong-hong
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy and safety of short-term treatment including fluoroquinolones anti-tuberculosis drugs for rifampicin resistant pulmonary tuberculosis (TB) in those areas carrying out the 'TB control project'. METHODS: TB cases involved in this study were from TB drug resistance ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19565883
データ提供:米国国立医学図書館(NLM)
Short-Term Treatment for Rifampicin-Resistant Pulmonary Tuberculosis: A Promising Approach
Tuberculosis (TB) remains a significant global health concern, and the emergence of drug resistance further complicates treatment. This study investigates the efficacy and safety of a short-term treatment regimen incorporating fluoroquinolones for rifampicin-resistant pulmonary TB. The authors conducted a randomized controlled trial in patients with rifampicin-resistant TB, comparing a treatment group receiving a regimen including fluoroquinolones to a control group receiving a standard re-treatment regimen. The results demonstrate that the short-term treatment group experienced a significantly higher sputum negative conversion rate compared to the control group. This research offers a glimmer of hope for the fight against drug-resistant TB, suggesting that incorporating fluoroquinolones may provide a more effective and efficient treatment strategy.
Fluoroquinolones: A Potential Breakthrough in TB Treatment
The study's findings provide compelling evidence for the potential benefits of incorporating fluoroquinolones into short-term treatment regimens for rifampicin-resistant pulmonary TB. The significantly higher sputum negative conversion rate observed in the treatment group suggests that fluoroquinolones may play a critical role in achieving successful treatment outcomes. These findings offer a beacon of hope for patients battling this challenging disease.
Fighting Drug-Resistant TB: A Collaborative Effort
The emergence of drug resistance in TB is a serious public health concern. The study's findings highlight the importance of ongoing research and innovation in developing effective treatment strategies for drug-resistant TB. It emphasizes the need for collaborative efforts involving researchers, clinicians, and public health officials to combat this global health challenge. It's a race against time, a journey across the vast desert of TB resistance, seeking an oasis of effective treatments.
Dr. Camel's Conclusion
This study offers a hopeful glimpse into the future of TB treatment. The promising results for the short-term treatment regimen incorporating fluoroquinolones suggest a potential shift in the fight against drug-resistant TB. Further research is essential to confirm these findings and explore the long-term impact of this treatment strategy, but it's a significant step forward in a battle that demands our continued vigilance.
Date :
- Date Completed 2009-11-10
- Date Revised 2013-11-21
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