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Long-term quality of life improvement in subjects with healed erosive esophagitis: treatment with lansoprazole.

Author: AtkinsonStuart, FrestonJames W, HaberMarian M, HuntBarbara, KovacsThomas O, PeuraDavid A

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Lansoprazole maintenance treatment for 12 months in healed erosive esophagitis subjects produced significantly greater improvements in quality of life indicators than ranitidine. These improvements were sustained during dose-titrated, open-label lansoprazole treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Gastroesophageal reflux disease (GERD) is a chronic symptomatic condition and may be associated with erosive esophagitis (EE). Considerable data on the long-term maintenance of healing of EE are available, but data on long-term GERD symptom prevention and patient quality of life (QOL) ar...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862958/

データ提供：米国国立医学図書館（NLM）

Long-Term Quality of Life Improvement with Lansoprazole: A Healing Oasis for Erosive Esophagitis

Gastroesophageal reflux disease (GERD) is a common condition that can lead to erosive esophagitis (EE). This study investigated the long-term effects of lansoprazole on quality of life (QOL) in patients with healed EE. The researchers conducted a double-blind maintenance treatment study comparing lansoprazole to ranitidine, followed by open-label lansoprazole therapy for up to 82 months. The results showed that lansoprazole treatment resulted in significantly greater improvements in QOL indicators compared to ranitidine, and these improvements were sustained during long-term open-label treatment.

Lansoprazole: A Long-Term Solution for GERD

This research provides compelling evidence for the long-term efficacy of lansoprazole in improving QOL in patients with healed EE. The study highlights the importance of maintenance therapy in preventing recurrence of EE and maintaining a high QOL.

Managing GERD: A Journey Through the Desert

GERD can be a constant source of discomfort, like a scorching sun beating down on you. This research offers a path to healing, providing a long-term oasis of relief for those struggling with this condition.

Dr.Camel's Conclusion

GERD can feel like a never-ending desert trek, with acid reflux like a sandstorm that follows you everywhere. This research provides a powerful camel, Lansoprazole, that can help you navigate the desert and find a lasting oasis of comfort.

Date :
  1. Date Completed 2010-06-17
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19582579

DOI: Digital Object Identifier

PMC2862958

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Languages

English

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