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Side-effects of pre-operative epirubicin-paclitaxel therapy in primary breast cancer associated with tumor biology.
Author: FischerThomas, HarbeckNadia, KatesRonald, ThomasAnke, WarmMathias
Original Abstract of the Article :
BACKGROUND: The objective of this analysis is to identify relationships between side-effects, tumor biological factors and response to pre-operative epirubicin and paclitaxel therapy in primary breast cancer. PATIENTS AND METHODS: The study was completed for 38 primary breast cancer patients (M0) w...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19596945
データ提供:米国国立医学図書館(NLM)
Exploring the Side Effects of Pre-Operative Epirubicin-Paclitaxel Therapy
This research delves into the intriguing world of breast cancer treatment. Specifically, it investigates the relationship between side effects, tumor biology, and the response to pre-operative epirubicin and paclitaxel therapy. The study meticulously analyzed data from 38 primary breast cancer patients who underwent this treatment, employing a meticulous approach to understand the complex interplay between treatment, tumor characteristics, and the patient's experience. The researchers discovered fascinating correlations between certain side effects and specific tumor biological factors, a finding that could greatly impact future personalized treatment approaches.
Personalized Treatment Approaches for Breast Cancer
This study reveals the intricate connection between the biological properties of a tumor and the side effects experienced by patients undergoing chemotherapy. Patients with negative estrogen or progesterone receptors, or high KI-67, were more likely to experience hair loss. Meanwhile, those with HER2-overexpressing tumors were less prone to severe nausea. These findings, like grains of sand shifting in the desert, reveal a pattern that could lead to more precise and tailored treatments for breast cancer patients.
The Importance of Understanding Tumor Biology
This study underscores the importance of understanding the biological properties of a tumor when developing treatment strategies. By considering the unique characteristics of each tumor, doctors can potentially predict and mitigate side effects, making the treatment experience more tolerable for patients. The findings, like a shimmering oasis in the desert, point to a future where breast cancer treatments are more effective and personalized.
Dr.Camel's Conclusion
This study sheds light on the fascinating link between tumor biology and the side effects experienced by breast cancer patients undergoing chemotherapy. Just as the desert reveals hidden secrets over time, this research reveals valuable insights that can guide future treatment strategies. By understanding these connections, doctors can create more personalized and effective treatments, making the journey through cancer treatment a little less harsh.
Date :
- Date Completed 2009-09-08
- Date Revised 2015-11-19
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English
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