Cyclosporine A eye drops inhibit the early-phase reaction in a type-I allergic conjunctivitis model in mice.

Author: KatsutaOsamu, NakamuraMasatsugu, OdaTomoko, ShiiDaisuke, ShinomiyaKatsuhiko

Paper Details 
Original Abstract of the Article :
PURPOSE: The effects of cyclosporine A eye drops on the early-phase reaction were investigated in a type-I allergic conjunctivitis model. METHODS: Mice were actively sensitized with ragweed (RW) absorbed on aluminium hydroxide gel and challenged with RW for 10 days (single challenge model) or 10-14...See full text at original site
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引用元:
https://doi.org/10.1089/jop.2009.0009

データ提供:米国国立医学図書館(NLM)

Cyclosporine A Eye Drops: A New Hope for Allergic Conjunctivitis

This study investigates the effects of cyclosporine A eye drops on the early-phase reaction in a type-I allergic conjunctivitis model in mice. The researchers evaluated the effects of cyclosporine A eye drops on increased vascular permeability, mast cell degranulation, and itching, comparing its efficacy to other anti-allergic eye drops. They found that cyclosporine A eye drops significantly inhibited the early-phase reaction, suggesting that it could be a valuable therapeutic agent for managing allergic conjunctivitis.

Cyclosporine A Eye Drops: A New Frontier in Allergic Conjunctivitis Treatment

This study offers promising results for treating allergic conjunctivitis, a common condition that affects millions worldwide. The researchers found that cyclosporine A eye drops effectively inhibited the early-phase reaction in a mouse model of allergic conjunctivitis, suggesting its potential for improving patient outcomes. This is particularly encouraging given the limited treatment options currently available for this condition.

Navigating the Sands of Allergic Conjunctivitis

Allergic conjunctivitis is a common condition that can significantly impact quality of life. This study explores the potential of cyclosporine A eye drops as a new treatment option, offering a glimmer of hope for those suffering from this frustrating condition. The findings suggest that cyclosporine A eye drops could be a valuable addition to the therapeutic arsenal for managing allergic conjunctivitis.

Dr.Camel's Conclusion

This study suggests that cyclosporine A eye drops could be a valuable new treatment for allergic conjunctivitis, effectively inhibiting the early-phase reaction. Further research is needed to confirm its effectiveness in clinical settings, but these findings offer a promising avenue for improving the lives of those affected by this condition.
Date :
  1. Date Completed 2009-10-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

19650707

DOI: Digital Object Identifier

10.1089/jop.2009.0009

Related Literature

SNS
PICO Info
in preparation
Languages

English

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