Beta-blockers and central nervous system side effects.

Author: CruickshankJ M, McAinshJ

Paper Details 
Original Abstract of the Article :
Beta-adrenergic blocking drugs are a widely used, well tolerated and effective treatment for a variety of cardiovascular and noncardiovascular disorders. Over the years, beta-blockers have been associated with an incidence, albeit low, of CNS side effects. The question of interest, however, is wheth...See full text at original site
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引用元:
https://doi.org/10.1016/0163-7258(90)90092-g

データ提供:米国国立医学図書館(NLM)

Beta-Blockers: A Desert Oasis for Cardiovascular Health, with Potential Side Effects

Beta-blockers, a widely used class of medications for cardiovascular disorders, are like a welcome oasis in the desert of heart disease. However, like any oasis, they may present some unexpected challenges. This research examines the potential central nervous system (CNS) side effects of beta-blockers, exploring the relationship between their lipophilicity (ability to dissolve in fats) and the occurrence of CNS side effects.

Navigating the Desert of Side Effects

The study finds that more lipophilic beta-blockers, like propranolol and pindolol, are more likely to cross the blood-brain barrier, potentially leading to CNS side effects such as sleep disturbances, nightmares, and hallucinations. This is like a desert traveler finding a pathway that leads to a different landscape, but potentially encountering unforeseen obstacles.

Staying Aware of the Desert's Terrain

While beta-blockers offer significant benefits for cardiovascular health, it is essential to be aware of potential side effects. Like a camel traversing a desert, it is important to be vigilant and consult with your healthcare provider to understand the potential risks and benefits of beta-blockers.

Dr. Camel's Conclusion

This research highlights the importance of considering the lipophilicity of beta-blockers when assessing potential CNS side effects. Like a camel carefully choosing its path in a desert, it is essential to work with your healthcare provider to find the right medication and dosage for your individual needs. Remember, like a desert oasis, beta-blockers can provide valuable support, but it is essential to be aware of the surrounding terrain.

Date :
  1. Date Completed 1990-04-30
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

1969642

DOI: Digital Object Identifier

10.1016/0163-7258(90)90092-g

Related Literature

SNS
PICO Info
in preparation
Languages

English

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