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Long-term endometrial effects in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES)--a randomised controlled trial of exemestane versus continued tamoxifen after 2-3 years tamoxifen.
Author: BertelliG, BlissJ M, CoombesR C, DrosikK, HallE, IrelandE, JassemJ, Karnicka-MlodkowskaH, SnowdonC F
Original Abstract of the Article :
The antiestrogen tamoxifen may have partial estrogen-like effects on the postmenopausal uterus. Aromatase inhibitors (AIs) are increasingly used after initial tamoxifen in the adjuvant treatment of postmenopausal early breast cancer due to their mechanism of action: a potential benefit being a reduc...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826098/
データ提供:米国国立医学図書館(NLM)
Aromatase Inhibitors for Breast Cancer: A Desert Oasis of Possibilities
Breast cancer, a challenging condition that affects many women, is like a sandstorm that can wreak havoc on the body. This study, conducted like a meticulous desert expedition, investigated the long-term effects of aromatase inhibitors, a type of medication used to treat breast cancer, on the uterus. They recruited postmenopausal women with early breast cancer and randomly assigned them to receive either exemestane, an aromatase inhibitor, or continued tamoxifen, another medication used for breast cancer treatment. The results were as clear as a desert sky after a dust storm: exemestane was associated with fewer uterine abnormalities compared to tamoxifen, highlighting its potential as a safer alternative for postmenopausal women with breast cancer. This study, like a well-preserved oasis in the desert, provides valuable information about the potential benefits of aromatase inhibitors in breast cancer treatment.Aromatase Inhibitors: A Desert Oasis of Uterine Health
This study, as vast as the desert itself, demonstrates that aromatase inhibitors may be associated with fewer uterine abnormalities compared to tamoxifen in postmenopausal women with early breast cancer. This finding, as clear as a desert well after a long trek, provides valuable information for clinicians and patients seeking to manage breast cancer while minimizing the risk of uterine complications.Breast Cancer and Aromatase Inhibitors: Navigating the Desert Landscape
Breast cancer is a complex condition, and finding the most effective and safe treatment is paramount. This study, like a well-marked trail in the desert, provides valuable information about the use of aromatase inhibitors in breast cancer treatment. The potential benefits of aromatase inhibitors, as clear as a desert sky at dawn, offer a new oasis of hope for those seeking to manage their breast cancer while minimizing potential risks.Dr. Camel's Conclusion
This study provides valuable insights into the long-term effects of aromatase inhibitors on the uterus in postmenopausal women with breast cancer. The findings, as clear as a desert sky after a sandstorm, suggest that aromatase inhibitors may offer a safer alternative to tamoxifen for managing breast cancer.Date :
- Date Completed 2010-05-13
- Date Revised 2021-10-20
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