Paper Details

  1. Home
  2. Paper Details

Comparative cognitive and subjective side effects of immediate-release oxycodone in healthy middle-aged and older adults.

Author: AmoryJohn K, CherrierMonique M, ErsekMary, RislerLinda, ShenDanny D

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

This study examined the effects of a single dose of oxycodone on thinking skills in healthy older and middle-aged adults. The results showed that oxycodone did impair cognitive function, but these effects were temporary and similar between the two age groups. This suggests that oxycodone may have similar cognitive effects in older and middle-aged adults without chronic pain.
Paper Details　
Original Abstract of the Article :
This study measured the objective and subjective neurocognitive effects of a single 10-mg dose of immediate-release oxycodone in healthy, older (> 65 years), and middle-aged (35 to 55 years) adults who were not suffering from chronic or significant daily pain. Seventy-one participants completed 2 se...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/19729346

データ提供：米国国立医学図書館（NLM）

Oxycodone's Effects on the Mind: A Tale of Two Age Groups

The human brain is a complex landscape, and understanding the effects of medications on our cognitive abilities is crucial. This study explores the impact of oxycodone, a common pain medication, on the minds of middle-aged and older adults. By comparing the neurocognitive effects of a single dose of oxycodone in these two age groups, the researchers offer valuable insights into the nuances of how this medication interacts with the brain.

Oxycodone's Impact on Attention, Memory, and Age

The study's findings show that a single dose of oxycodone can have a significant impact on cognitive function, affecting attention, working memory, and verbal memory in both middle-aged and older adults. The researchers also discovered that the two age groups exhibited similar responses to the medication, suggesting that oxycodone's effects on cognitive function may not vary significantly with age. This is like finding a hidden oasis in the desert where both young and old can rest and rejuvenate.

Navigating the Desert of Pain Management

This study emphasizes the importance of carefully considering the cognitive effects of medications, especially when managing pain. It highlights the need for individualized approaches to pain management, taking into account a patient's age and cognitive function. The findings are like a map in the desert - guiding us towards a more informed and personalized approach to pain relief.

Dr. Camel's Conclusion

This study provides valuable insights into the neurocognitive effects of oxycodone in middle-aged and older adults. The findings underscore the importance of personalized pain management strategies, taking into account individual differences in cognitive function. It's like discovering a new oasis in the desert - a place where we can find the best possible solutions for managing pain while preserving cognitive well-being.

Date :
  1. Date Completed 2010-01-08
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19729346

DOI: Digital Object Identifier

NIHMS112930

Related Literature

Article Analysis
・Side Effects of oxycodone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.