The safety of sumatriptan and naratriptan in pregnancy: what have we learned?

Author: ChurchillPaige, CunningtonMarianne, EphrossSara

Paper Details 
Original Abstract of the Article :
OBJECTIVES: To monitor for a signal of major teratogenicity by determining the risk of all major defects following in utero exposure to sumatriptan and naratriptan. To monitor for unusual patterns of birth defects that might suggest teratogenicity. BACKGROUND: The prevalence of migraine is highest ...See full text at original site
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引用元:
https://doi.org/10.1111/j.1526-4610.2009.01529.x

データ提供:米国国立医学図書館(NLM)

The Safety of Sumatriptan and Naratriptan During Pregnancy: A Journey Through Uncertainty

Migraine, a debilitating headache disorder, can cast a shadow over a woman's pregnancy, creating a desert of uncertainty and concern. This research delves into the safety of sumatriptan and naratriptan, two commonly prescribed medications for migraine, during pregnancy, seeking to provide reassurance and guidance.

The authors meticulously analyzed data from the Sumatriptan and Naratriptan Pregnancy Registry, a database designed to monitor the safety of these drugs during pregnancy. They assessed the incidence of major birth defects among infants exposed to these medications in utero. The authors found no significant increase in the risk of major birth defects following exposure to sumatriptan during pregnancy, providing reassurance for women seeking migraine relief during this crucial period.

Navigating the Desert of Uncertainty: A Reassuring Perspective

This research provides a much-needed oasis of reassurance for women with migraine seeking relief during pregnancy. The authors' findings suggest that sumatriptan, when used appropriately, does not appear to increase the risk of major birth defects, offering peace of mind for both mothers and their healthcare providers.

The Importance of Safe and Effective Migraine Management During Pregnancy

Migraine can significantly impact a woman's quality of life, particularly during pregnancy. This research offers valuable information for guiding the safe and effective management of migraine during this sensitive period. The authors' findings suggest that sumatriptan, when used appropriately, does not appear to pose a significant risk to the developing fetus, offering a potential option for migraine relief during pregnancy.

Dr. Camel's Conclusion

This research serves as a beacon of hope in the desert of uncertainty surrounding the safety of migraine medications during pregnancy. The authors' findings suggest that sumatriptan, when used appropriately, does not appear to increase the risk of major birth defects, providing reassurance for women seeking migraine relief during this critical period. The study emphasizes the importance of open communication between patients and their healthcare providers to ensure safe and effective migraine management throughout pregnancy.

Date :
  1. Date Completed 2011-08-04
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

19804390

DOI: Digital Object Identifier

10.1111/j.1526-4610.2009.01529.x

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SNS
PICO Info
in preparation
Languages

English

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