A double-blind comparison of bisoprolol and captopril for treatment of essential hypertension in the elderly.

Author: AlbertiA, BracchettiD, BrunelliA, CantelliI, GradnikR, LeonardiG, OrselliL, PavesiP C

Paper Details 
Original Abstract of the Article :
The aim of the study was to compare the antihypertensive efficacy and safety of a new beta blocker with high beta 1 selectivity, bisoprolol, with captopril in 28 elderly patients, aged over 65 years, with mild-to-moderate essential hypertension (WHO classes I and II). After a placebo run-in period o...See full text at original site
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引用元:
https://doi.org/10.1007/BF01857642

データ提供:米国国立医学図書館(NLM)

Comparing Bisoprolol and Captopril for High Blood Pressure in Seniors

This research delves into the realm of geriatric hypertension, a significant challenge in the field of medicine. The study employed a double-blind crossover design to assess the efficacy and safety of bisoprolol, a selective beta-blocker, against captopril, an angiotensin-converting enzyme (ACE) inhibitor, in elderly individuals with mild to moderate hypertension. The researchers discovered that both medications effectively lowered blood pressure, with bisoprolol demonstrating a greater reduction in heart rate compared to captopril. These findings provide valuable insights into the therapeutic options for managing hypertension in the elderly population.

Both Bisoprolol and Captopril Show Promise in Lowering Blood Pressure

The results indicate that both bisoprolol and captopril were effective in lowering blood pressure in elderly patients, achieving a reduction in diastolic blood pressure to 95 mmHg or less in a significant percentage of patients. This highlights the potential of both medications for managing hypertension in this age group, which is particularly important considering the increased risk of cardiovascular complications in older adults.

Understanding the Effects of Different Medications

The study demonstrates that different medications may have distinct effects on blood pressure and heart rate. While both bisoprolol and captopril effectively lowered blood pressure, bisoprolol demonstrated a greater reduction in heart rate. This finding underscores the importance of considering the individual patient's needs and potential side effects when selecting an appropriate medication for hypertension management.

Dr.Camel's Conclusion

Just like a camel navigating through a vast and diverse landscape, finding the right medication for high blood pressure can be a journey with twists and turns. This study provides crucial information for healthcare professionals navigating the treatment options for older adults with hypertension. While both bisoprolol and captopril showed promise, the study's findings suggest bisoprolol may be a better choice for those needing a stronger heart rate control. Remember, a well-informed decision alongside a healthcare professional is the key to a healthy heart.

Date :
  1. Date Completed 1991-03-22
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

1981017

DOI: Digital Object Identifier

10.1007/BF01857642

Related Literature

SNS
PICO Info
in preparation
Languages

English

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