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Vitamin D compounds for people with chronic kidney disease requiring dialysis.

Author: CraigJonathan C, ElderGrahame, MacaskillPetra, McGregorDavid O, PalmerSuetonia C, StrippoliGiovanni Fm

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Guidelines recommend vitamin D for managing chronic kidney disease (CKD) by lowering parathyroid hormone levels, but this treatment may increase phosphorus and calcium levels, which have been linked to higher death rates in observational studies. However, these studies also suggest that vitamin D treatment may be linked to lower death rates in CKD.
Paper Details　
Original Abstract of the Article :
Clinical guidelines recommend vitamin D compounds to suppress serum parathyroid hormone (PTH) in chronic kidney disease (CKD), however treatment may be associated with increased serum phosphorus and calcium, which are associated with increased mortality in observational studies. Observational data a...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/14651858.CD005633.pub2

データ提供：米国国立医学図書館（NLM）

Vitamin D Compounds: A Complex Landscape for People with CKD

Chronic kidney disease (CKD), a growing health concern, often requires dialysis to manage. This research examines the role of vitamin D compounds in CKD patients requiring dialysis. The study explores the benefits and potential risks of vitamin D therapy, specifically focusing on its impact on serum parathyroid hormone (PTH), calcium, and phosphorus levels.

Navigating the Fine Line of Vitamin D Therapy

The study reveals a complex relationship between vitamin D therapy and CKD patients. While vitamin D compounds are recommended for suppressing PTH levels, they can also lead to increased serum phosphorus and calcium, which have been associated with increased mortality. Furthermore, observational data suggest a possible independent association between vitamin D therapy and reduced mortality in CKD.

Personalized Approach to Vitamin D Therapy

This research emphasizes the need for a personalized approach to vitamin D therapy in CKD patients. The study underscores the importance of carefully considering the individual patient's needs, potential benefits, and risks before initiating vitamin D therapy. Imagine a desert landscape where the path to optimal health is paved with complex factors. This research provides a roadmap for navigating the nuanced landscape of vitamin D therapy for CKD patients.

Dr.Camel's Conclusion

This study highlights the complexities of vitamin D therapy in CKD patients, emphasizing the need for a tailored approach based on individual patient factors. This research is like exploring a vast desert, where the path to optimal health requires careful consideration of the unique needs of each individual traveler.
Date :
  1. Date Completed 2010-01-27
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

19821349

DOI: Digital Object Identifier

10.1002/14651858.CD005633.pub2

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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