A randomized controlled trial of pentazocine versus ondansetron for the treatment of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.

Author: CharuluxanananSomrat, PatumanondJayanton, PunjasawadwongYodying, SriprajittichaiPin, TamdeeDecha, TawichasriChamaiporn

Paper Details 
Original Abstract of the Article :
Ondansetron is effective for the treatment of intrathecal morphine-induced pruritus. There is evidence that kappa-opioid receptor agonists have antipruritic activity. Pentazocine is an agonist of kappa-opioid receptors and partial agonist at mu-opioid receptors. We therefore performed a randomized, ...See full text at original site
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引用元:
https://doi.org/10.1213/ANE.0b013e3181b72e93

データ提供:米国国立医学図書館(NLM)

Relief from the Itch: A New Oasis in the Desert of Postpartum Pain

Intrathecal morphine, a common pain management technique used during cesarean delivery, can sometimes lead to a persistent and uncomfortable itching sensation. This study explores the efficacy of pentazocine, a kappa-opioid receptor agonist, in treating intrathecal morphine-induced pruritus. The authors compared the effectiveness of pentazocine and ondansetron, a serotonin antagonist, in relieving pruritus in patients undergoing cesarean delivery. The study aimed to assess the potential benefits of pentazocine as an alternative treatment option for this challenging side effect.

A New Path to Relief

This study suggests that pentazocine may offer a promising alternative for treating intrathecal morphine-induced pruritus. The findings indicate that pentazocine was equally effective as ondansetron in relieving itching, suggesting its potential as a valuable treatment option for postpartum patients experiencing this uncomfortable side effect.

A More Comfortable Recovery

The study's findings suggest that pentazocine could improve the overall recovery experience for postpartum patients. By effectively managing pruritus, clinicians can help patients achieve a more comfortable and enjoyable recovery period.

Dr. Camel's Conclusion

This research explores the potential of pentazocine as an effective treatment for intrathecal morphine-induced pruritus. The findings suggest that pentazocine may offer a valuable alternative to ondansetron, providing relief from this uncomfortable side effect and improving the overall postpartum recovery experience for patients.

Date :
  1. Date Completed 2009-11-05
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

19843798

DOI: Digital Object Identifier

10.1213/ANE.0b013e3181b72e93

Related Literature

SNS
PICO Info
in preparation
Languages

English

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