A fatality due to cyproheptadine and citalopram.

Author: HargroveVeronica, MolinaD Kimberley

Paper Details 
Original Abstract of the Article :
Cyproheptadine (Periactin) is a first-generation antihistamine available in over-the-counter cold medications and is used to treat allergic-type symptoms. Although antihistamines in general have long been known to cause serious side effects, especially when taken in overdose, few reports that specif...See full text at original site
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引用元:
https://doi.org/10.1093/jat/33.8.564

データ提供:米国国立医学図書館(NLM)

A Fatality Due to Cyproheptadine and Citalopram: A Cautionary Tale

This study presents a tragic case report, highlighting the potential dangers of combining cyproheptadine, an over-the-counter antihistamine, with citalopram, an antidepressant. The report investigates the death of a 42-year-old woman, revealing that the cause of death was cyproheptadine and citalopram intoxication. This case study emphasizes the importance of understanding the potential interactions between medications, particularly when combining over-the-counter and prescription drugs. It underscores the crucial role of patient education and healthcare professional awareness in preventing drug-related fatalities.

A Deadly Combination: Cyproheptadine and Citalopram

The case report highlights the lethal consequences of combining cyproheptadine and citalopram. The study found that the woman's blood and tissue samples contained significant concentrations of both drugs, leading to the conclusion that the cause of death was drug intoxication. This case serves as a cautionary tale, highlighting the importance of understanding potential drug interactions and the risks associated with combining medications, especially when taking over-the-counter drugs with prescription medications.

Navigating the Desert of Drug Interactions

Imagine a desert traveler navigating a landscape filled with hidden dangers. Drug interactions can be similarly treacherous, lurking beneath the surface and posing potential risks. This case report emphasizes the importance of transparency with healthcare providers, fully disclosing all medications being taken, including over-the-counter drugs. It also underscores the need for healthcare professionals to be vigilant in assessing potential drug interactions and advising patients accordingly.

Dr. Camel's Conclusion

This tragic case serves as a powerful reminder that drug interactions can be dangerous, even when combining over-the-counter and prescription medications. Just as a desert traveler must be vigilant about hidden dangers, so too must we be mindful of potential drug interactions. By fostering open communication between patients and healthcare providers, and by emphasizing the importance of careful medication monitoring, we can help prevent such tragic outcomes.

Date :
  1. Date Completed 2010-01-05
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

19874671

DOI: Digital Object Identifier

10.1093/jat/33.8.564

Related Literature

SNS
PICO Info
in preparation
Languages

English

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