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Successful retreatment with alitretinoin in patients with relapsed chronic hand eczema.
Author: BissonnetteR, BrownT C, CambazardF, GerlachB, GuentherL, MaaresJ, RuzickaT, WormM
Original Abstract of the Article :
BACKGROUND: Patients with severe chronic hand eczema (CHE) often respond to therapy with oral alitretinoin (9-cis retinoic acid). However, the efficacy of alitretinoin after disease relapse has not been demonstrated. OBJECTIVES: To assess the efficacy and safety of a second course of oral alitretin...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1111/j.1365-2133.2009.09572.x
データ提供:米国国立医学図書館(NLM)
Retreatment with Alitretinoin: A Renewed Oasis in the Desert of Chronic Hand Eczema
Chronic hand eczema (CHE) is a persistent and often debilitating condition, a vast and arid desert of discomfort for those afflicted. This double-blind study, like a resourceful traveler seeking a cure, evaluates the efficacy and safety of retreatment with alitretinoin for patients experiencing a relapse of CHE. The researchers focus on patients who had previously responded well to alitretinoin but had experienced a relapse, making retreatment a crucial area of investigation. The study meticulously compares the effects of alitretinoin at two different dosages to placebo, monitoring patient responses and safety outcomes.
A Renewed Hope in the Desert of Eczema
The study's findings, like a life-giving spring in the desert, demonstrate the effectiveness of retreatment with alitretinoin in patients with relapsed CHE. A significant majority of patients who received alitretinoin experienced a positive response, achieving clear or almost clear hands. These results offer a renewed hope for patients struggling with this challenging condition, providing a potential avenue for long-term management.
Navigating the Desert of Eczema Treatment
This study highlights the potential of intermittent treatment with alitretinoin as a valuable approach for managing CHE. It encourages us to explore alternative treatment strategies and consider the long-term implications of medication use. The desert of eczema research continues to evolve, and we must adapt our approaches to offer the most effective care for those seeking relief from this persistent condition.
Dr.Camel's Conclusion
This study demonstrates the effectiveness of retreatment with alitretinoin in patients with relapsed CHE. It offers a valuable approach for long-term management, providing a potential oasis of relief in the arid desert of this challenging condition.
Date :
- Date Completed 2010-05-26
- Date Revised 2018-12-01
Further Info :
Related Literature
English
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