Carbamazepine but not pregabalin impairs eye control: a study on acute objective CNS side effects in healthy volunteers.

Author: FeddersenBerend, HüttenbrennerAngelika, NoachtarSoheyl, RémiJan

Paper Details 
Original Abstract of the Article :
PURPOSE: This prospective study compared the effects of the new antiepileptic drug (AED) pregabalin (PGB) with the established AED carbamazepine (CBZ) on eye movements and posture control. METHODS: Eye movements and posture control after AED intake were studied by electrooculography and posturograp...See full text at original site
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引用元:
https://doi.org/10.1016/j.eplepsyres.2009.10.007

データ提供:米国国立医学図書館(NLM)

Carbamazepine and Pregabalin: A Comparison of Their Effects on Eye Control

Antiepileptic drugs, like a compass guiding a traveler through the desert, are crucial for managing epilepsy. This study compared the effects of two antiepileptic drugs, carbamazepine (CBZ) and pregabalin (PGB), on eye movements and posture control in healthy volunteers. It's like observing the effects of different types of sand on the movement of a caravan.

Carbamazepine's Impact on Eye Movements

The study found that CBZ, but not PGB, impaired saccadic eye movements, the rapid eye movements that allow us to focus on different objects. This is like observing how a different type of sand might hinder the movement of a caravan's wheels. The authors concluded that CBZ caused more slowing of the peak horizontal saccade than PGB.

Navigating the Side Effects of Antiepileptic Drugs

This study provides valuable insights into the potential side effects of antiepileptic drugs. It highlights the importance of considering the specific effects of different medications on various aspects of neurological function. It's like understanding the different obstacles that a caravan might encounter in the desert and preparing for them accordingly.

Dr.Camel's Conclusion

This research emphasizes the importance of careful consideration of drug effects and side effects in clinical practice. It's a reminder that even seemingly subtle differences in medication can have significant impacts on neurological function. This underscores the need for continuous research and monitoring to ensure the safe and effective use of medications.

Date :
  1. Date Completed 2010-05-03
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

19926254

DOI: Digital Object Identifier

10.1016/j.eplepsyres.2009.10.007

SNS
PICO Info
in preparation
Languages

English

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