Dose response effects of zolpidem in normal geriatric subjects.

Author: KaffemanM, KrallR, MaylebenD W, OchsR, ScharfM B

Paper Details 
Original Abstract of the Article :
The dose-related hypnotic effects and effects on memory, performance, and daytime alertness of zolpidem 5, 10, 15, and 20 mg were compared with those of placebo in 30 elderly non-insomniac volunteers in a randomized, placebo-controlled, three-period crossover study. Subjects were randomized into two...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1993640

データ提供:米国国立医学図書館(NLM)

Zolpidem: A Safe and Effective Sleep Aid for Seniors

Sleep is a vital oasis in the desert of life, offering respite and rejuvenation. This research explores the effects of zolpidem, a hypnotic drug, on normal geriatric subjects. The study carefully analyzes the dose-response effects of zolpidem, examining its impact on sleep quality, memory, performance, and daytime alertness. By exploring the nuances of zolpidem's effects, the study aims to provide a clearer understanding of its potential as a safe and effective sleep aid for older adults.

Zolpidem: A Gentle Oasis in the Desert of Sleeplessness

The study demonstrated that zolpidem, across various dosages, significantly decreased sleep latency and increased sleep efficiency in elderly participants. Subjective reports confirmed improved sleep quality and duration. Importantly, the study found no consistent effects on memory or performance, suggesting that zolpidem's benefits may not come at the cost of cognitive impairment. The study also found no evidence of rebound insomnia after discontinuation of zolpidem.

Promoting Healthy Sleep for Seniors

This research provides valuable insights into the use of zolpidem as a sleep aid for older adults. The findings suggest that zolpidem can be a safe and effective option for promoting healthy sleep in this population, while minimizing potential cognitive side effects. However, as with any medication, it's crucial to discuss with a healthcare professional to determine the appropriate dosage and ensure safe and effective use.

Dr.Camel's Conclusion

This research offers a gentle breeze in the desert of sleeplessness for seniors, suggesting that zolpidem can be a valuable tool for promoting restful nights. The study's findings provide a roadmap for safer and more effective sleep management in this population. As we continue to explore the vast desert of sleep disorders, we can use this research to navigate towards more peaceful slumber for all.

Date :
  1. Date Completed 1991-03-21
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

1993640

DOI: Digital Object Identifier

1993640

Related Literature

SNS
PICO Info
in preparation
Languages

English

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