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Predicting short term response to anti-inflammatory therapy in young children with asthma.

Author: ChristmannMartin, Dogan-YildizGülben, KloskaMagdalena, LiebAdrian, RoseMarkus A, RosewichMartin, SchubertRalf, SchulzeJohannes, ZielenStefan

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Pre-bronchodilatory FEV1 and airway reversibility are good indicators of short-term anti-inflammatory therapy in young children with asthma. Both fluticasone and montelukast were equally effective in this age group.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Currently available anti-inflammatory treatment for young children with asthma includes inhaled corticosteroids (ICS) and the leukotriene receptor antagonist (LTRA) montelukast. OBJECTIVE: To evaluate potential biomarkers of predicting short-term (6-week) response to ICS and LTRAs in ch...See full text at original site
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引用元：
https://doi.org/10.1185/03007990903485148

データ提供：米国国立医学図書館（NLM）

Predicting Asthma Response: A Guiding Star for Treatment

Asthma, a chronic lung condition that affects millions, requires careful management and tailored treatment strategies. This research explores potential biomarkers that can predict short-term response to anti-inflammatory therapies in young children with asthma. The authors conducted a study, meticulously evaluating the effectiveness of inhaled corticosteroids (ICS) and leukotriene receptor antagonists (LTRAs) in a group of children with episodic asthma. Their findings identify key biomarkers that can help clinicians tailor treatment approaches to maximize the effectiveness of anti-inflammatory therapies.

Biomarkers: Guiding the Path to Asthma Control

The study reveals that pre-bronchodilatory FEV1 and airway reversibility are strong predictors of short-term response to anti-inflammatory therapies in young children with asthma. This finding offers valuable insights into the potential for using these biomarkers to personalize treatment strategies and optimize asthma control in this patient population.

Navigating the Desert of Asthma

Asthma is a complex condition that requires careful management and individualized treatment strategies. This research offers valuable tools for navigating the desert of asthma management, helping clinicians tailor treatment approaches to maximize effectiveness and improve asthma control in young children.

Dr. Camel's Conclusion

This study provides valuable insights into the potential for using pre-bronchodilatory FEV1 and airway reversibility as biomarkers to predict short-term response to anti-inflammatory therapies in young children with asthma. These findings offer a promising roadmap for personalizing treatment strategies and improving asthma control in this patient population. As a researcher, I am always seeking to improve the lives of those affected by asthma, and this study offers valuable guidance for optimizing treatment approaches and improving asthma control.

Date :
  1. Date Completed 2010-04-30
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

20001651

DOI: Digital Object Identifier

10.1185/03007990903485148

Related Literature

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・Effective treatment of asthma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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