H1-antihistamines and oxidative burst of professional phagocytes.

Author: CizMilan, DrabikovaKatarina, JancinovaViera, LojekAntonin, MacickovaTatiana, MoravcovaJana, NosalRadomir, PecivovaJana

Paper Details 
Original Abstract of the Article :
OBJECTIVES: We analysed and compared the effect of five H1-antihistamines on stimulated oxidative burst at extra- and intracellular level of isolated and stimulated human polymorphonuclear leukocytes. DESIGN: Oxidative burst of isolated human neutrophils was studied by means of luminol and isolumin...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/20027159

データ提供:米国国立医学図書館(NLM)

H1-Antihistamines and the Immune Desert: A Quest for Balance

The immune system, a crucial defense mechanism against invaders, is like a vigilant protector in the vast desert of our body. This research explores the impact of H1-antihistamines, medications commonly used to treat allergies, on the immune response, particularly the oxidative burst of professional phagocytes, those cells that engulf and destroy pathogens.

H1-Antihistamines: A Complex Role in Immune Response

The study reveals that H1-antihistamines can suppress the oxidative burst of neutrophils, cells that are crucial for fighting infections. This effect varies depending on the specific H1-antihistamine used. It's like different types of desert plants having different tolerances to drought conditions. While these medications are effective for treating allergy symptoms, their impact on the immune response needs to be carefully considered.

Balancing Immune Function and Allergy Relief

This research underscores the need for a balanced approach when using H1-antihistamines. While they can effectively relieve allergy symptoms, their effects on the immune system deserve careful consideration. It's like finding the delicate balance between protecting the oasis from drought and promoting the growth of necessary plants. Further research is needed to understand the long-term implications of H1-antihistamine use on immune function.

Dr. Camel's Conclusion

This study provides valuable insights into the complex interplay between H1-antihistamines and the immune system. It highlights the need for a balanced approach to managing allergy symptoms while maintaining optimal immune function. As we continue to explore the vast desert of immunology, we must strive to understand the subtle nuances of how different medications influence our body's defenses.
Date :
  1. Date Completed 2010-05-24
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

20027159

DOI: Digital Object Identifier

NEL300709A22

Related Literature

SNS
PICO Info
in preparation
Languages

English

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