Patients with panic disorder unaccompanied by depression improve with alprazolam and imipramine treatment.

Author: ArgyleN, DeltitoJ A, KlermanG L

Paper Details 
Original Abstract of the Article :
Patients with panic disorder (N = 1168) were enrolled in a multicenter, 8-week, double-blind clinical trial of imipramine, alprazolam, and placebo to analyze whether the effectiveness of these agents is dependent on the depressive/dysphoric symptomatology which often coexists in panic disorder patie...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2005075

データ提供:米国国立医学図書館(NLM)

Panic Disorder: A Desert of Anxiety

Navigating the vast desert of mental health, we often encounter the challenging terrain of panic disorder. This research delves into the therapeutic landscape, investigating the effectiveness of alprazolam and imipramine in treating panic disorder, particularly in individuals without accompanying depression. The study employed a double-blind clinical trial with a large sample of participants (N=1168). The researchers aimed to determine whether the efficacy of these medications is influenced by the presence of depression, a common companion to panic disorder. They conducted analyses on the entire sample and a carefully selected subsample (N=312) free of depression and dysphoria. The findings revealed a remarkable insight: the response to imipramine or alprazolam was independent of depressive symptoms in both groups. This implies that the absence of depression does not hinder the effectiveness of these medications for panic disorder.

A Oasis of Hope for Panic Sufferers

The results of this research offer a beacon of hope for individuals struggling with panic disorder. They suggest that even without the presence of depression, these medications can provide relief from the debilitating symptoms of panic attacks. This finding is particularly significant considering the high prevalence of panic disorder and the often-misunderstood nature of the condition.

Navigating the Desert of Anxiety with Alprazolam and Imipramine

This research sheds light on the potential of alprazolam and imipramine for treating panic disorder, even in the absence of depression. However, it is crucial to consult with a healthcare professional for individualized treatment plans. They can assess your specific needs and determine the best course of action. Remember, like navigating the vast desert, seeking guidance and support is essential in managing this condition.

Dr.Camel's Conclusion

This research reminds us that panic disorder can manifest in different ways, and treatment should be tailored to each individual's needs. It's a reminder that we should treat each patient as unique, just as we treat each desert oasis as a precious source of life.

Date :
  1. Date Completed 1991-04-25
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

2005075

DOI: Digital Object Identifier

2005075

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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