Evaluation of the subjective and reinforcing effects of diphenhydramine, levetiracetam, and valproic acid.

Author: FeltnerDouglas E, HaigGeorge

Paper Details 
Original Abstract of the Article :
Few unscheduled sedating medications have been evaluated for their subjective and reinforcing effects in humans. To increase the information available about unscheduled sedating medications and to evaluate the ability of human laboratory measures to discriminate between scheduled and unscheduled sed...See full text at original site
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引用元:
https://doi.org/10.1177/0269881109359095

データ提供:米国国立医学図書館(NLM)

Exploring the Subjective and Reinforcing Effects of Sedative Medications

The realm of [pharmacology] is constantly searching for a deeper understanding of the effects of medications on the human body. This study investigates the subjective and reinforcing effects of several sedative medications, including diphenhydramine, levetiracetam, valproic acid, and diazepam. The research delves into the complex relationship between these drugs and their potential for abuse, a topic that requires careful consideration and exploration.

A Comparative Study of Sedative Medications

The study found that diazepam produced significantly greater subjective and reinforcing effects than placebo, suggesting a higher potential for abuse. This is like a camel encountering a mirage in the desert – a tempting illusion that can be dangerous if not approached cautiously. Levetiracetam also showed some evidence of abuse potential, while diphenhydramine and valproic acid exhibited lower levels of abuse potential. The study's findings provide valuable insights into the relative abuse potential of these medications and underscore the importance of careful prescription and monitoring.

Understanding the Potential Risks and Benefits

This research highlights the importance of understanding the potential for abuse associated with even seemingly harmless medications. It's like a camel navigating through a desert filled with hidden dangers – some may seem harmless, but a careful assessment is crucial for survival. The study's findings can help clinicians make more informed decisions about prescribing these medications, minimizing the risk of misuse and ensuring the safety of patients.

Dr. Camel's Conclusion

This study sheds light on the complex relationship between sedative medications and their potential for abuse. It provides important insights that can help clinicians make more informed decisions about prescribing these medications. Like a camel navigating the unpredictable desert, we must approach these medications with careful consideration and be aware of the potential risks and benefits.

Date :
  1. Date Completed 2011-09-28
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

20147572

DOI: Digital Object Identifier

10.1177/0269881109359095

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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