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The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder.

Author: AndreassenOle A, BergsholmPer, KesslerUte, MaltUlrik F, MorkenGunnar, OedegaardKetil J, SchøyenHelle, VaalerArne E

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Treating depression in bipolar disorder is challenging. The effectiveness of commonly used antidepressants for this condition is unclear. While electroconvulsive therapy is considered the most effective treatment, there are no controlled studies on its use for bipolar depression. While electroconvulsive therapy is generally safe, its effects on cognition are debated. This study aims to compare the effectiveness and side effects of electroconvulsive therapy to medication for treatment-resistant bipolar depression, assessing changes in thinking and quality of life during treatment.
Paper Details　
Original Abstract of the Article :
The treatment of depressive phases of bipolar disorder is challenging. The effects of the commonly used antidepressants in bipolar depression are questionable. Electroconvulsive therapy is generally considered to be the most effective treatment even if there are no randomized controlled trials of el...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847998/

データ提供：米国国立医学図書館（NLM）

Electroconvulsive Therapy: A Controversial but Potentially Effective Treatment for Bipolar Depression

Bipolar disorder is a complex mental health condition characterized by alternating episodes of mania and depression. This study investigates the effectiveness of electroconvulsive therapy (ECT) in treating treatment-resistant depression in bipolar disorder. The researchers designed a randomized controlled trial to compare the effects of ECT to pharmacological treatment in patients with bipolar depression who had not responded to conventional therapies. Their aim was to assess the efficacy and safety of ECT in this challenging population.

The study highlights the potential benefits of ECT as a treatment option for treatment-resistant depression in bipolar disorder. While ECT remains a controversial treatment, the researchers emphasize the need for more research to fully understand its effectiveness and safety in this patient population. The study also emphasizes the importance of careful consideration of treatment options and patient preferences when addressing treatment-resistant bipolar depression.

Electroconvulsive Therapy: A Potential Solution for Treatment-Resistant Depression

This study sheds light on the potential of ECT as a treatment option for bipolar depression, particularly in cases where conventional therapies have failed. While ECT remains a controversial treatment, the researchers highlight the need for more research to fully understand its effectiveness and safety in this patient population.

Weighing the Risks and Benefits of ECT

It's essential to have a thorough discussion with a healthcare professional to understand the potential risks and benefits of ECT. Just as a desert traveler must carefully consider the challenges of a long journey, patients considering ECT must weigh the potential benefits against the possible risks and side effects.

Dr. Camel's Conclusion

This study underscores the importance of exploring different treatment options for treatment-resistant bipolar depression. While ECT remains a controversial treatment, the researchers highlight the need for more research to understand its effectiveness and safety. This research is like uncovering a hidden oasis in the vast desert of bipolar disorder treatment, offering hope for new and effective therapeutic approaches.

Date :
  1. Date Completed 2010-05-06
  2. Date Revised 2023-11-03
Further Info :

Pubmed ID

20178636

DOI: Digital Object Identifier

PMC2847998

Related Literature

Article Analysis
・Effective treatment of bipolar disorder
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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