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Drug delivery strategies for therapy of visceral leishmaniasis.

Author: GuptaSwati, PalAjay, VyasSuresh P

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study reviews the challenges of treating visceral leishmaniasis (VL), a potentially fatal disease, and explores the potential of colloidal carriers as drug delivery systems (DDSs) for antileishmanial compounds. While AmBisome is the only DDS currently used for VL, research continues to seek better solutions.
Paper Details　
Original Abstract of the Article :
Visceral leishmaniasis (VL) is the most overwhelming type of leishmaniasis associated with the poverty of developing countries and usually mortal if untreated. Most of the conventionally used dosage forms offer us the shortcomings of toxic side effects and emergence of drug resistance. Several effor...See full text at original site
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引用元：
https://doi.org/10.1517/17425240903548232

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Visceral Leishmaniasis Treatment

Visceral leishmaniasis (VL), a parasitic disease that often flourishes in the harsh deserts of poverty and neglect, poses a significant threat to global health. This study explores the challenges of treating VL, emphasizing the need for improved drug delivery strategies to combat this formidable foe.

Drug Delivery: Finding the Oasis of Efficacy in VL Treatment

This research, like a caravan seeking a reliable source of water in the desert, highlights the critical need for effective drug delivery strategies in VL treatment. The study delves into the limitations of conventional approaches, emphasizing the need for novel drug delivery systems (DDSs) to improve efficacy and minimize side effects.

Colloidal Carriers: A Potential Oasis for VL Treatment

This research, like a well-placed oasis in the desert, explores the potential of colloidal carriers as DDSs for VL treatment. The study's findings suggest that these carriers, targeting macrophage-rich organs, could offer a promising avenue for delivering antileishmanial compounds with greater efficacy and reduced side effects.

Dr. Camel's Conclusion

VL, a disease that thrives in the harsh deserts of poverty and neglect, presents a significant challenge for researchers seeking effective treatment options. This study underscores the importance of innovative drug delivery strategies, highlighting the potential of colloidal carriers to provide a much-needed oasis of hope in the fight against this debilitating disease.

Date :
  1. Date Completed 2010-06-03
  2. Date Revised 2010-03-05
Further Info :

Pubmed ID

20201740

DOI: Digital Object Identifier

10.1517/17425240903548232

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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